MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3065 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
mmr (requalified) — multidrug resistance protein Mmr mmr Rv3066 (family_assigned) — TetR/AcrR family transcriptional regulator Rv3066 Rv3064c (family_assigned) — DoxX family protein Rv3064c Rv3067 (family_assigned) — hypothetical protein Rv3067 guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA Rv1217c (family_assigned) — multidrug efflux ABC transporter permease Rv1217c Rv3728 (requalified) — MFS transporter Rv3728 hemL (requalified) — glutamate-1-semialdehyde 2%2C1-aminomutase hemL Rv3000 (family_assigned) — ABC transporter permease Rv3000 efpA (requalified) — multidrug efflux MFS transporter EfpA efpA jefA (requalified) — multidrug efflux pump JefA jefA Rv0849 (requalified) — MFS transporter Rv0849 Rv1995 (family_assigned) — hemerythrin domain-containing protein Rv1995 Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 sirR (family_assigned) — manganese-binding transcriptional regulator MntR sirR Rv1725c (family_assigned) — winged helix-turn-helix transcriptional regulator Rv1725c mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv1167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1167c eccA1 (family_assigned) — type VII secretion system ESX-1 AAA family ATPase eccA1 eccA3 (requalified) — ESX-3 secretion system protein EccA eccA3 Rv0435c (family_assigned) — AAA family ATPase Rv0435c ctpE (requalified) — cation-translocating P-type ATPase ctpE Rv3091 (family_assigned) — patatin-like phospholipase family protein Rv3091 atsA (requalified) — arylsulfatase AtsA atsA kstD (requalified) — 3-oxosteroid 1-dehydrogenase kstD Rv0145 (requalified) — class I SAM-dependent methyltransferase Rv0145 guaB2 (requalified) — IMP dehydrogenase guaB2 guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 apt (requalified) — adenine phosphoribosyltransferase apt argS (requalified) — arginine--tRNA ligase argS rplK (requalified) — 50S ribosomal protein L11 rplK Rv1218c (family_assigned) — multidrug efflux ABC transporter ATP-binding prote Rv1218c Rv1216c (family_assigned) — isoprenylcysteine carboxylmethyltransferase family Rv1216c raaS (family_assigned) — transcriptional regulator RaaS raaS Rv1215c (family_assigned) — CocE/NonD family hydrolase Rv1215c Rv1686c (family_assigned) — ABC transporter permease Rv1686c Rv1220c (requalified) — methyltransferase Rv1220c Rv1714 (family_assigned) — SDR family oxidoreductase Rv1714 fadB3 (requalified) — 3-hydroxybutyryl-CoA dehydrogenase FadB fadB3 Rv1716 (family_assigned) — hypothetical protein Rv1716 Rv1718 (requalified) — 3-keto-5-aminohexanoate cleavage protein Rv1718 Rv1358 (family_assigned) — LuxR C-terminal-related transcriptional regulator Rv1358 Rv3727 (requalified) — FAD-dependent oxidoreductase Rv3727 hemB (requalified) — porphobilinogen synthase hemB hemA (requalified) — glutamyl-tRNA reductase hemA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.