MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3058c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3058c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3058c Rv3057c (family_assigned) — SDR family oxidoreductase Rv3057c cyp136 (requalified) — cytochrome P450 cyp136 Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c pirG (requalified) — exported repetitive protein pirG Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv3492c (requalified) — Mce associated protein Rv3492c TB18.5 (family_assigned) — hypothetical protein TB18.5 Rv1836c (family_assigned) — substrate-binding domain-containing protein Rv1836c mce4A (family_assigned) — Mce family protein Mce4A mce4A nrdB (requalified) — R2-like ligand-binding oxidase nrdB aac (requalified) — aminoglycoside 2'-N-acetyltransferase aac eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 Rv0927c (family_assigned) — SDR family oxidoreductase Rv0927c Rv1714 (family_assigned) — SDR family oxidoreductase Rv1714 Rv3485c (requalified) — short-chain type dehydrogenase/reductase Rv3485c Rv3530c (family_assigned) — SDR family oxidoreductase Rv3530c pks13 (requalified) — polyketide synthase Pks13 pks13 mbtE (requalified) — peptide synthetase mbtE Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 polA (requalified) — DNA polymerase I polA Rv0272c (family_assigned) — alpha/beta hydrolase Rv0272c Rv0274 (family_assigned) — VOC family protein Rv0274 mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv0674 (family_assigned) — PaaX family transcriptional regulator C-terminal d Rv0674 trcR (requalified) — two-component system response regulator TrcR trcR moxR3 (family_assigned) — MoxR family ATPase moxR3 Rv2721c (family_assigned) — LGFP repeat-containing protein Rv2721c Rv0312 (family_assigned) — Hsp70 family protein Rv0312 fbpC (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpC ripA (family_assigned) — NlpC/P60 family peptidoglycan endopeptidase RipA ripA Rv1158c (dark) — hypothetical protein Rv1158c mtc28 (family_assigned) — LpqN/LpqT family lipoprotein mtc28 eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 htpG (requalified) — molecular chaperone HtpG htpG mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 grpE (requalified) — nucleotide exchange factor GrpE grpE dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 mce4D (family_assigned) — virulence factor Mce family protein mce4D lprN (family_assigned) — Mce family lipoprotein LprN lprN mce4F (family_assigned) — virulence factor Mce family protein mce4F Rv3493c (requalified) — mammalian cell entry protein Rv3493c mce4C (family_assigned) — virulence factor Mce family protein mce4C Rv0163 (family_assigned) — thioesterase family protein Rv0163 adhE1 (family_assigned) — zinc-type alcohol dehydrogenase subunit E adhE1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.