MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3022A · 45 genes shown · anchor PPE48 · open gene page → · ← back to 1 hop

Evidence: Min score 0
PE29 (family_assigned) — PE family protein PE29 PE29 PPE46 (family_assigned) — PPE family protein PPE46 PPE46 esxS (requalified) — ESAT-6 like protein EsxS esxS esxQ (requalified) — type VII secretion system ESX-3 effector EsxQ esxQ esxR (family_assigned) — WXG100 family type VII secretion target esxR PPE67 (family_assigned) — PPE family protein PPE67 PPE67 ruvX (requalified) — Holliday junction resolvase RuvX ruvX alaS (requalified) — alanine--tRNA ligase alaS PE20 (family_assigned) — PE family protein PE20 PE20 tatB (requalified) — Sec-independent protein translocase protein TatB tatB PE27A (family_assigned) — PE family protein PE27A PE27A Rv3737 (family_assigned) — threonine/serine exporter family protein Rv3737 Rv2738c (family_assigned) — DUF3046 domain-containing protein Rv2738c esxH (requalified) — type VII secretion system effector EsxH esxH esxV (requalified) — ESAT-6 like protein EsxV esxV esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB esxG (requalified) — type VII secretion system protein EsxG esxG eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 PPE66 (family_assigned) — PPE family protein PPE66 PPE66 Rv3740c (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr Rv3740c Rv3741c (requalified) — oxidoreductase Rv3741c Rv3742c (requalified) — oxidoreductase Rv3742c PE25 (family_assigned) — PE family protein PE25 PE25 aroE (requalified) — shikimate dehydrogenase aroE mltG (requalified) — endolytic transglycosylase MltG mltG Rv2551c (family_assigned) — A24 family peptidase Rv2551c Rv2556c (requalified) — secondary thiamine-phosphate synthase enzyme YjbQ Rv2556c Rv0038 (family_assigned) — YqgE/AlgH family protein Rv0038 Rv1691 (family_assigned) — hypothetical protein Rv1691 Rv3529c (requalified) — TLR2-mediated response inhibitor Rv3529c Rv2267c (requalified) — sulfotransferase Rv2267c PPE31 (family_assigned) — PPE family protein PPE31 PPE31 Rv1805c (dark) — hypothetical protein Rv1805c PPE32 (family_assigned) — PPE family protein PPE32 PPE32 PPE33 (family_assigned) — PPE family protein PPE33 PPE33 PPE44 (family_assigned) — PPE family protein PPE44 PPE44 htrA (requalified) — serine protease HtrA htrA guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA tatC (family_assigned) — twin-arginine translocase subunit TatC tatC rseA (requalified) — anti-sigma E factor RseA rseA Rv1337 (family_assigned) — rhomboid family intramembrane serine protease Rv1337 sigE (requalified) — RNA polymerase sigma factor SigE sigE PE_PGRS60 (family_assigned) — PE-PGRS family-related protein PE_PGRS60 PE_PGRS60 PE10 (family_assigned) — PE family protein PE10 PE10

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.