MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3001c · 28 genes shown · anchor ilvN · open gene page → · ← back to 1 hop

Evidence: Min score 0
ilvC (requalified) — ketol-acid reductoisomerase ilvC ilvN (family_assigned) — acetolactate synthase small subunit ilvN ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 ilvD (requalified) — dihydroxy-acid dehydratase ilvD ilvB2 (family_assigned) — thiamine pyrophosphate-binding protein ilvB2 ilvG (requalified) — acetolactate synthase ilvG ilvX (family_assigned) — acetolactate synthase large subunit ilvX leuD (family_assigned) — 3-isopropylmalate dehydratase small subunit leuD leuB (requalified) — 3-isopropylmalate dehydrogenase leuB leuC (family_assigned) — 3-isopropylmalate dehydratase large subunit leuC leuA (requalified) — 2-isopropylmalate synthase leuA mhpE (requalified) — 4-hydroxy-2-oxovalerate aldolase mhpE thrC (requalified) — threonine synthase thrC ilvA (requalified) — threonine ammonia-lyase ilvA ilvE (requalified) — branched-chain amino acid aminotransferase ilvE aspC (requalified) — pyridoxal phosphate-dependent aminotransferase aspC Rv2989 (family_assigned) — IclR family transcriptional regulator Rv2989 serA1 (requalified) — D-3-phosphoglycerate dehydrogenase serA1 hsaG (requalified) — acetaldehyde dehydrogenase (acetylating) hsaG accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 hsaE (requalified) — 2-keto-4-pentenoate hydratase hsaE hsaF (requalified) — 4-hydroxy-2-oxovalerate aldolase hsaF Rv3468c (requalified) — dTDP-glucose 4,6-dehydratase Rv3468c thrB (requalified) — homoserine kinase thrB thrA (requalified) — homoserine dehydrogenase thrA serC (requalified) — phosphoserine transaminase serC argS (requalified) — arginine--tRNA ligase argS lysA (requalified) — diaminopimelate decarboxylase lysA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.