MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2987c · 44 genes shown · anchor leuC · open gene page → · ← back to 1 hop

Evidence: Min score 0
leuD (family_assigned) — 3-isopropylmalate dehydratase small subunit leuD leuC (family_assigned) — 3-isopropylmalate dehydratase large subunit leuC leuB (requalified) — 3-isopropylmalate dehydrogenase leuB leuA (requalified) — 2-isopropylmalate synthase leuA Rv2989 (family_assigned) — IclR family transcriptional regulator Rv2989 ilvC (requalified) — ketol-acid reductoisomerase ilvC ilvD (requalified) — dihydroxy-acid dehydratase ilvD ilvN (family_assigned) — acetolactate synthase small subunit ilvN mez (requalified) — NAD-dependent malic enzyme mez Rv2454c (family_assigned) — 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2454c Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c pykA (requalified) — pyruvate kinase pykA ppdK (requalified) — pyruvate%2C phosphate dikinase ppdK serA1 (requalified) — D-3-phosphoglycerate dehydrogenase serA1 ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 ilvB2 (family_assigned) — thiamine pyrophosphate-binding protein ilvB2 hsaG (requalified) — acetaldehyde dehydrogenase (acetylating) hsaG ilvE (requalified) — branched-chain amino acid aminotransferase ilvE accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 Rv0264c (family_assigned) — allophanate hydrolase subunit 1 Rv0264c Rv0263c (family_assigned) — 5-oxoprolinase/urea amidolyase family protein Rv0263c Rv2239c (family_assigned) — hypothetical protein Rv2239c hupB (family_assigned) — DNA-binding protein HupB hupB ilvG (requalified) — acetolactate synthase ilvG ilvX (family_assigned) — acetolactate synthase large subunit ilvX aspC (requalified) — pyridoxal phosphate-dependent aminotransferase aspC mdh (requalified) — malate dehydrogenase mdh fum (requalified) — class II fumarate hydratase fum bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB pca (requalified) — pyruvate carboxylase pca glcB (requalified) — malate synthase G glcB mobA (requalified) — molybdenum cofactor guanylyltransferase mobA icd2 (requalified) — NADP-dependent isocitrate dehydrogenase icd2 pta (requalified) — phosphate acetyltransferase pta sucD (family_assigned) — succinyl-CoA ligase subunit alpha sucD aroF (requalified) — chorismate synthase aroF sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC eno (requalified) — phosphopyruvate hydratase eno rplJ (requalified) — 50S ribosomal protein L10 rplJ rplX (requalified) — 50S ribosomal protein L24 rplX rplB (requalified) — 50S ribosomal protein L2 rplB rplE (requalified) — 50S ribosomal protein L5 rplE rplF (requalified) — 50S ribosomal protein L6 rplF Rv1126c (family_assigned) — MarR family transcriptional regulator Rv1126c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.