MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2970A · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2970A (family_assigned) — hypothetical protein Rv2970A Rv2971 (requalified) — aldo/keto reductase Rv2971 lipN (requalified) — lipase/esterase LipN lipN metH (requalified) — methionine synthase metH Rv2969c (requalified) — mycothiol-dependent reductase Rv2969c Rv2968c (family_assigned) — vitamin K epoxide reductase family protein Rv2968c Rv2298 (requalified) — aldo/keto reductase Rv2298 otsB1 (requalified) — trehalose-6-phosphate phosphatase OtsB otsB1 sodC (family_assigned) — superoxide dismutase family protein sodC mas (requalified) — mycocerosate synthase mas Rv1597 (family_assigned) — methyltransferase domain-containing protein Rv1597 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks12 (requalified) — type I polyketide synthase pks12 accD5 (family_assigned) — acyl-CoA carboxylase subunit beta accD5 pca (requalified) — pyruvate carboxylase pca rsmD (requalified) — 16S rRNA (guanine(966)-N(2))-methyltransferase Rsm rsmD Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c metB (requalified) — cystathionine gamma-synthase metB metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC sahH (requalified) — adenosylhomocysteinase sahH eno (requalified) — phosphopyruvate hydratase eno rlmB (requalified) — 23S rRNA (guanosine(2251)-2'-O)-methyltransferase rlmB tsnR (requalified) — RNA methyltransferase tsnR Rv0881 (requalified) — RNA methyltransferase Rv0881 Rv0380c (requalified) — RNA methyltransferase Rv0380c otsB2 (requalified) — trehalose-phosphatase otsB2 treS (requalified) — maltose alpha-D-glucosyltransferase treS treZ (requalified) — malto-oligosyltrehalose trehalohydrolase treZ Rv3401 (family_assigned) — glycoside hydrolase family 65 protein Rv3401 Rv2004c (family_assigned) — AAA family ATPase Rv2004c Rv2402 (requalified) — trehalase Rv2402 Rv2876 (requalified) — transmembrane protein Rv2876 qcrA (requalified) — hypothetical protein qcrA qcrB (family_assigned) — cytochrome bc complex cytochrome b subunit qcrB Rv0433 (requalified) — glutamate--cysteine ligase Rv0433 ctaD (family_assigned) — cytochrome c oxidase subunit I ctaD ctaC (family_assigned) — cytochrome c oxidase subunit II ctaC fas (requalified) — fatty acid synthase fas fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC nadC (requalified) — carboxylating nicotinate-nucleotide diphosphorylas nadC nadB (requalified) — L-aspartate oxidase nadB nadA (requalified) — quinolinate synthetase A nadA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.