MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2949c · 46 genes shown · anchor fadD22 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 fadD29 (requalified) — long-chain-fatty-acid--AMP ligase FadD29 fadD29 pks15 (requalified) — polyketide synthase pks15 entC (requalified) — isochorismate synthase entC Rv0948c (requalified) — chorismate mutase Rv0948c Rv1885c (requalified) — chorismate mutase Rv1885c trpE (requalified) — anthranilate synthase component I trpE aroF (requalified) — chorismate synthase aroF hisC1 (requalified) — histidinol-phosphate aminotransferase hisC1 hisC2 (requalified) — histidinol-phosphate transaminase hisC2 cobC (requalified) — aminotransferase cobC pks1 (requalified) — polyketide synthase pks1 mas (requalified) — mycocerosate synthase mas ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB mbtE (requalified) — peptide synthetase mbtE pks17 (requalified) — polyketide synthase pks17 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB menD (requalified) — 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1 menD mbtI (requalified) — salicylate synthase mbtI mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA aroG (requalified) — 3-deoxy-7-phosphoheptulonate synthase class II aroG tyrA (requalified) — prephenate dehydrogenase TyrA tyrA pheA (requalified) — prephenate dehydratase pheA fbpB (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpB trpG (requalified) — anthranilate synthase component II trpG trpD (requalified) — anthranilate phosphoribosyltransferase trpD trpC (requalified) — indole-3-glycerol phosphate synthase TrpC trpC trpA (family_assigned) — tryptophan synthase subunit alpha trpA trpB (family_assigned) — tryptophan synthase subunit beta trpB aroB (requalified) — 3-dehydroquinate synthase aroB aroA (requalified) — 3-phosphoshikimate 1-carboxyvinyltransferase aroA aroK (requalified) — shikimate kinase AroK aroK Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB hisD (requalified) — histidinol dehydrogenase hisD hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI Rv2230c (requalified) — Nif3-like dinuclear metal center hexameric protein Rv2230c cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB cobQ1 (requalified) — cobyric acid synthase cobQ1 fas (requalified) — fatty acid synthase fas mbtC (requalified) — polyketide synthetase MbtC mbtC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.