MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2765 · 45 genes shown · anchor dfrA · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2765 (family_assigned) — dienelactone hydrolase family protein Rv2765 Rv2054 (family_assigned) — dienelactone hydrolase family protein Rv2054 dfrA (requalified) — dihydrofolate reductase dfrA Rv2762c (family_assigned) — winged helix-turn-helix domain-containing protein Rv2762c Rv3192 (family_assigned) — hypothetical protein Rv3192 thyA (requalified) — thymidylate synthase ThyA thyA gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB hsdS (family_assigned) — restriction endonuclease subunit S hsdS thyX (requalified) — FAD-dependent thymidylate synthase thyX Rv3254 (requalified) — oxidoreductase Rv3254 spoU (requalified) — tRNA (cytidine(34)-2'-O)-methyltransferase spoU malQ (requalified) — 4-alpha-glucanotransferase malQ fxsA (family_assigned) — FxsA family protein fxsA Rv2052c (requalified) — amidohydrolase Rv2052c glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 fmt (requalified) — methionyl-tRNA formyltransferase fmt purN (requalified) — phosphoribosylglycinamide formyltransferase purN vapC42 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC42 vapB42 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB42 hsdM (requalified) — class I SAM-dependent DNA methyltransferase hsdM Rv3368c (family_assigned) — nitroreductase family protein Rv3368c Rv1907c (dark) — hypothetical protein Rv1907c Rv0245 (family_assigned) — flavin reductase family protein Rv0245 Rv1939 (family_assigned) — flavin reductase family protein Rv1939 hsaB (family_assigned) — flavin-dependent monooxygenase reductase subunit H hsaB dut (requalified) — deoxyuridine 5'-triphosphate nucleotidohydrolase dut folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD tmk (requalified) — dTMP kinase tmk gcvH (requalified) — glycine cleavage system protein GcvH gcvH gcvT (requalified) — aminomethyltransferase gcvT Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c purD (requalified) — phosphoribosylamine--glycine ligase purD vapC21 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC21 ptrp (family_assigned) — hypothetical protein ptrp iniR (family_assigned) — isoniazid response ATPase/transcriptional regulato iniR Rv2164c (family_assigned) — hypothetical protein Rv2164c erg3 (requalified) — membrane-bound C-5 sterol desaturase erg3 ureD (requalified) — urease accessory protein UreD ureD Rv3732 (dark) — DUF2330 domain-containing protein Rv3732 mfpA (requalified) — pentapeptide repeat protein MfpA mfpA Rv3365c (requalified) — sensor histidine kinase Rv3365c tig (requalified) — trigger factor tig Rv3363c (family_assigned) — DUF742 domain-containing protein Rv3363c Rv3362c (family_assigned) — ATP/GTP-binding protein Rv3362c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.