MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2764c · 44 genes shown · anchor dfrA · open gene page → · ← back to 1 hop

Evidence: Min score 0
thyA (requalified) — thymidylate synthase ThyA thyA dfrA (requalified) — dihydrofolate reductase dfrA thyX (requalified) — FAD-dependent thymidylate synthase thyX dut (requalified) — deoxyuridine 5'-triphosphate nucleotidohydrolase dut folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD tmk (requalified) — dTMP kinase tmk glyA1 (requalified) — serine hydroxymethyltransferase glyA1 glyA2 (requalified) — serine hydroxymethyltransferase glyA2 gcvT (requalified) — aminomethyltransferase gcvT gpm2 (requalified) — phosphoglycerate mutase gpm2 folC (requalified) — bifunctional tetrahydrofolate synthase/dihydrofola folC Rv2762c (family_assigned) — winged helix-turn-helix domain-containing protein Rv2762c rnhB (requalified) — ribonuclease HII rnhB fmt (requalified) — methionyl-tRNA formyltransferase fmt purN (requalified) — phosphoribosylglycinamide formyltransferase purN lprE (family_assigned) — LppP/LprE family lipoprotein lprE ndkA (requalified) — nucleoside-diphosphate kinase ndkA dcd (requalified) — dCTP deaminase dcd purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH nrdE (family_assigned) — ribonucleoside-diphosphate reductase subunit alpha nrdE nrdZ (requalified) — adenosylcobalamin-dependent ribonucleoside-diphosp nrdZ gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB gcvH (requalified) — glycine cleavage system protein GcvH gcvH sdaA (requalified) — L-serine ammonia-lyase sdaA lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC entC (requalified) — isochorismate synthase entC Rv3213c (family_assigned) — AAA family ATPase Rv3213c pfkA (requalified) — ATP-dependent 6-phosphofructokinase pfkA pgi (requalified) — glucose-6-phosphate isomerase pgi fba (requalified) — class II fructose-bisphosphate aldolase fba folP1 (requalified) — dihydropteroate synthase folP1 folP2 (requalified) — dihydropteroate synthase folP2 valS (requalified) — valine--tRNA ligase valS Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c hsdS (family_assigned) — restriction endonuclease subunit S hsdS vapC42 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC42 vapB42 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB42 hsdM (requalified) — class I SAM-dependent DNA methyltransferase hsdM lepB (requalified) — signal peptidase I lepB rplS (requalified) — 50S ribosomal protein L19 rplS dnaN (family_assigned) — DNA polymerase III subunit beta dnaN lppK (family_assigned) — hypothetical protein lppK Rv2901c (dark) — DUF2469 domain-containing protein Rv2901c coaE (requalified) — dephospho-CoA kinase coaE

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.