MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2757c · 44 genes shown · anchor vapB21 · open gene page → · ← back to 1 hop

Evidence: Min score 0
vapC21 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC21 vapB21 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB21 hsdM (requalified) — class I SAM-dependent DNA methyltransferase hsdM vapC42 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC42 vapB42 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB42 hsdS (family_assigned) — restriction endonuclease subunit S hsdS Rv2762c (family_assigned) — winged helix-turn-helix domain-containing protein Rv2762c vapC26 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC26 dfrA (requalified) — dihydrofolate reductase dfrA chaA (requalified) — calcium:proton antiporter chaA vapB47 (requalified) — antitoxin VapB47 vapB47 vapB2 (requalified) — type II toxin-antitoxin system antitoxin VapB2 vapB2 thyX (requalified) — FAD-dependent thymidylate synthase thyX dapA (requalified) — 4-hydroxy-tetrahydrodipicolinate synthase dapA vapB30 (requalified) — type II toxin-antitoxin system antitoxin VapB30 vapB30 vapB34 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB34 Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ Rv3488 (family_assigned) — PadR family transcriptional regulator Rv3488 thyA (requalified) — thymidylate synthase ThyA thyA vapB26 (requalified) — type II toxin-antitoxin system antitoxin VapB26 vapB26 Rv0580c (requalified) — mycobacterial cell wall protein Rv0580c Rv0580c Rv3387 (requalified) — transposase Rv3387 Rv2961 (requalified) — transposase Rv2961 vapC18 (family_assigned) — PIN domain nuclease vapC18 glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 fmt (requalified) — methionyl-tRNA formyltransferase fmt purN (requalified) — phosphoribosylglycinamide formyltransferase purN hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF impA (family_assigned) — inositol monophosphatase family protein impA hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH vapC47 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC47 vapC35 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC35 vapC46 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC46 Rv3406 (requalified) — alpha-ketoglutarate-dependent sulfate ester dioxyg Rv3406 vapC8 (family_assigned) — PIN domain-containing protein vapC8 vapC1 (requalified) — type II toxin-antitoxin system ribonuclease VapC1 vapC1 vapC2 (family_assigned) — PIN domain nuclease vapC2 Rv0299 (requalified) — toxin-antitoxin system toxin Rv0299 Rv0298 (family_assigned) — ribbon-helix-helix protein%2C CopG family Rv0298 Rv0302 (family_assigned) — TetR/AcrR family transcriptional regulator Rv0302

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.