MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2698 · 46 genes shown · anchor dut · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2698 (dark) — DUF3093 domain-containing protein Rv2698 Rv2696c (dark) — DUF3710 domain-containing protein Rv2696c dut (requalified) — deoxyuridine 5'-triphosphate nucleotidohydrolase dut Rv2235 (family_assigned) — SURF1 family protein Rv2235 eccB4 (family_assigned) — type VII secretion system ESX-4 subunit EccB4 eccB4 eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 Rv0948c (requalified) — chorismate mutase Rv0948c eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 TB9.4 (family_assigned) — hypothetical protein TB9.4 qcrA (requalified) — hypothetical protein qcrA mycP5 (requalified) — type VII secretion system ESX-5 serine protease my mycP5 Rv2975c (family_assigned) — hypothetical protein Rv2975c Rv1474c (family_assigned) — helix-turn-helix domain-containing protein Rv1474c rbpA (family_assigned) — RNA polymerase-binding protein RbpA rbpA Rv2413c (family_assigned) — DNA polymerase III subunit delta Rv2413c Rv1830 (family_assigned) — HTH-type transcriptional regulator Rv1830 Rv2708c (family_assigned) — hypothetical protein Rv2708c lprE (family_assigned) — LppP/LprE family lipoprotein lprE thyA (requalified) — thymidylate synthase ThyA thyA tmk (requalified) — dTMP kinase tmk ndkA (requalified) — nucleoside-diphosphate kinase ndkA thyX (requalified) — FAD-dependent thymidylate synthase thyX dcd (requalified) — dCTP deaminase dcd Rv1456c (requalified) — heme A synthase Rv1456c ptpA (requalified) — protein-tyrosine-phosphatase ptpA ptkA (family_assigned) — protein tyrosine kinase transcriptional regulator ptkA Rv2229c (family_assigned) — zinc ribbon domain-containing protein Rv2229c Rv2228c (requalified) — multifunctional RNASE H/alpha-ribazole phosphatase Rv2228c Rv2230c (requalified) — Nif3-like dinuclear metal center hexameric protein Rv2230c eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 Rv3657c (family_assigned) — membrane protein Rv3657c mycP2 (requalified) — type VII secretion system ESX-2 serine protease my mycP2 cut3 (family_assigned) — cutinase family protein cut3 mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 aroG (requalified) — 3-deoxy-7-phosphoheptulonate synthase class II aroG aroF (requalified) — chorismate synthase aroF tyrA (requalified) — prephenate dehydrogenase TyrA tyrA pheA (requalified) — prephenate dehydratase pheA trpE (requalified) — anthranilate synthase component I trpE Rv1885c (requalified) — chorismate mutase Rv1885c eccD5 (family_assigned) — type VII secretion system ESX-5 subunit EccD5 eccD5 eccC5 (requalified) — ESX-5 type VII secretion system protein EccC5 eccC5 eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.