MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2687c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2687c (family_assigned) — fluoroquinolone transporter permease Rv2687c Rv2686c (family_assigned) — fluoroquinolones efflux ABC transporter permease Rv2686c Rv2688c (family_assigned) — ABC transporter ATP-binding protein Rv2688c Rv1978 (requalified) — class I SAM-dependent methyltransferase Rv1978 Rv0210 (family_assigned) — hypothetical protein Rv0210 rsmA (requalified) — anti-sigma-M factor RsmA rsmA Rv0955 (family_assigned) — DUF6350 family protein Rv0955 papA3 (requalified) — acyltransferase PapA3 papA3 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv0097 (family_assigned) — TauD/TfdA family dioxygenase Rv0097 Rv0849 (requalified) — MFS transporter Rv0849 papA1 (requalified) — acyltransferase PapA1 papA1 Rv0804 (family_assigned) — CPBP family intramembrane glutamic endopeptidase Rv0804 Rv1272c (family_assigned) — fatty acid ABC transporter ATP-binding protein/per Rv1272c irtB (family_assigned) — iron ABC transporter ATP-binding protein/permease irtB irtA (family_assigned) — iron ABC transporter ATP-binding protein/permease irtA Rv0194 (family_assigned) — ABC transporter ATP-binding protein Rv0194 Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c Rv0209 (family_assigned) — hypothetical protein Rv0209 trmB (requalified) — tRNA (guanosine(46)-N7)-methyltransferase TrmB trmB Rv0207c (family_assigned) — NYN domain-containing protein Rv0207c Rv2474c (family_assigned) — hypothetical protein Rv2474c rsdA (requalified) — anti-sigma D factor RsdA rsdA sigM (requalified) — ECF RNA polymerase sigma factor SigM sigM Rv3909 (dark) — hypothetical protein Rv3909 murJ (requalified) — murein biosynthesis integral membrane protein MurJ murJ mutT4 (requalified) — NUDIX hydrolase mutT4 trxC (requalified) — thioredoxin trxC trxB2 (requalified) — thioredoxin-disulfide reductase trxB2 Rv0954 (requalified) — DUF5336 domain-containing protein Rv0954 mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG purN (requalified) — phosphoribosylglycinamide formyltransferase purN purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH pimE (requalified) — mannosyltransferase pimE mmpL10 (requalified) — RND transporter MmpL10 mmpL10 pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 mas (requalified) — mycocerosate synthase mas fas (requalified) — fatty acid synthase fas ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10 fcoT (requalified) — fatty acyl CoA thioesterase FcoT fcoT nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp Rv0100 (requalified) — acyl carrier protein Rv0100

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.