MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2678c · 40 genes shown · anchor hemY · open gene page → · ← back to 1 hop

Evidence: Min score 0
hemE (requalified) — uroporphyrinogen decarboxylase hemE hemY (requalified) — protoporphyrinogen oxidase hemY hemC (requalified) — hydroxymethylbilane synthase hemC hemZ (requalified) — ferrochelatase hemZ hemD (requalified) — uroporphyrin-III C-methyltransferase hemD hemQ (requalified) — hydrogen peroxide-dependent heme synthase hemQ cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG Rv0260c (requalified) — uroporphyrinogen-III synthase Rv0260c Rv2675c (requalified) — class I SAM-dependent methyltransferase Rv2675c echA15 (family_assigned) — enoyl-CoA hydratase/isomerase family protein echA15 hemB (requalified) — porphobilinogen synthase hemB Rv2680 (dark) — DUF3000 domain-containing protein Rv2680 Rv2681 (requalified) — ribonuclease D Rv2681 Rv2850c (family_assigned) — magnesium chelatase subunit D family protein Rv2850c Rv0958 (family_assigned) — ATP-binding protein Rv0958 hemA (requalified) — glutamyl-tRNA reductase hemA mmcO (requalified) — multicopper oxidase MmcO mmcO cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ Rv0514 (dark) — hypothetical protein Rv0514 Rv0259c (family_assigned) — sirohydrochlorin chelatase Rv0259c cysC (requalified) — adenylyl-sulfate kinase cysC narK3 (requalified) — nitrate/nitrite transporter narK3 Rv2751 (requalified) — class I SAM-dependent methyltransferase Rv2751 Rv3707c (requalified) — hypothetical protein Rv3707c fadE7 (requalified) — acyl-CoA dehydrogenase fadE7 fadE2 (requalified) — acyl-CoA dehydrogenase fadE2 fadE23 (family_assigned) — acyl-CoA dehydrogenase family protein fadE23 fadE1 (requalified) — acyl-CoA dehydrogenase FadE1 fadE1 fadE4 (family_assigned) — acyl-CoA dehydrogenase family protein fadE4 fadE13 (family_assigned) — acyl-CoA dehydrogenase family protein fadE13 hemL (requalified) — glutamate-1-semialdehyde 2%2C1-aminomutase hemL Rv0513 (family_assigned) — DUF3093 domain-containing protein Rv0513 Rv2413c (family_assigned) — DNA polymerase III subunit delta Rv2413c Rv2256c (dark) — hypothetical protein Rv2256c rbpA (family_assigned) — RNA polymerase-binding protein RbpA rbpA rphA (requalified) — ribonuclease PH rphA rpsA (requalified) — 30S ribosomal protein S1 rpsA rpsD (requalified) — 30S ribosomal protein S4 rpsD rpsK (requalified) — 30S ribosomal protein S11 rpsK rplD (requalified) — 50S ribosomal protein L4 rplD

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.