MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2675c · 36 genes shown · anchor hemE · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2675c (requalified) — class I SAM-dependent methyltransferase Rv2675c hemE (requalified) — uroporphyrinogen decarboxylase hemE hemQ (requalified) — hydrogen peroxide-dependent heme synthase hemQ hemY (requalified) — protoporphyrinogen oxidase hemY echA15 (family_assigned) — enoyl-CoA hydratase/isomerase family protein echA15 Rv2751 (requalified) — class I SAM-dependent methyltransferase Rv2751 Rv3707c (requalified) — hypothetical protein Rv3707c Rv2743c (family_assigned) — hypothetical protein Rv2743c hemC (requalified) — hydroxymethylbilane synthase hemC hemZ (requalified) — ferrochelatase hemZ hemD (requalified) — uroporphyrin-III C-methyltransferase hemD cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG Rv2680 (dark) — DUF3000 domain-containing protein Rv2680 Rv2850c (family_assigned) — magnesium chelatase subunit D family protein Rv2850c Rv0958 (family_assigned) — ATP-binding protein Rv0958 fadE7 (requalified) — acyl-CoA dehydrogenase fadE7 fadE2 (requalified) — acyl-CoA dehydrogenase fadE2 fadE23 (family_assigned) — acyl-CoA dehydrogenase family protein fadE23 fadE1 (requalified) — acyl-CoA dehydrogenase FadE1 fadE1 fadE4 (family_assigned) — acyl-CoA dehydrogenase family protein fadE4 fadE13 (family_assigned) — acyl-CoA dehydrogenase family protein fadE13 Rv2750 (family_assigned) — Rv2750 family mycofactocin-dependent SDR oxidoredu Rv2750 Rv2749 (family_assigned) — putative quinol monooxygenase Rv2749 Rv1896c (requalified) — class I SAM-dependent methyltransferase Rv1896c Rv3767c (requalified) — class I SAM-dependent methyltransferase Rv3767c Rv0893c (requalified) — class I SAM-dependent methyltransferase Rv0893c Rv0281 (requalified) — class I SAM-dependent methyltransferase Rv0281 pirG (requalified) — exported repetitive protein pirG eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 ask (requalified) — aspartate kinase ask asd (requalified) — aspartate-semialdehyde dehydrogenase asd lpqF (requalified) — serine hydrolase lpqF 35kd_ag (family_assigned) — hypothetical protein 35kd_ag lppL (family_assigned) — hypothetical protein lppL chiZ (requalified) — cell wall hydrolase ChiZ chiZ lmeA (requalified) — mannan chain length control protein LmeA lmeA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.