MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2633c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2633c (requalified) — non-heme di-iron catalase Rv2633c Rv2632c (family_assigned) — DUF1876 domain-containing protein Rv2632c Rv3896c (requalified) — transglycosylase Rv3896c Rv0955 (family_assigned) — DUF6350 family protein Rv0955 Rv1978 (requalified) — class I SAM-dependent methyltransferase Rv1978 Rv0688 (requalified) — FAD/NAD(P)-binding oxidoreductase Rv0688 Rv1869c (requalified) — FAD-dependent oxidoreductase Rv1869c nirB (family_assigned) — nitrite reductase large subunit NirB nirB Rv0804 (family_assigned) — CPBP family intramembrane glutamic endopeptidase Rv0804 cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c Rv3074 (family_assigned) — DUF222 domain-containing protein Rv3074 Rv1378c (family_assigned) — hypothetical protein Rv1378c Rv2302 (family_assigned) — DUF1918 domain-containing protein Rv2302 Rv1366 (family_assigned) — GTP pyrophosphokinase family protein Rv1366 Rv3131 (requalified) — NAD(P)H nitroreductase Rv3131 Rv3134c (requalified) — universal stress protein Rv3134c dosT (requalified) — two-component system sensor histidine kinase DosT dosT eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2 eccB2 (family_assigned) — type VII secretion system ESX-2 subunit EccB2 eccB2 Rv1733c (family_assigned) — hypothetical protein Rv1733c Rv3786c (family_assigned) — peptidoglycan DD-metalloendopeptidase family prote Rv3786c Rv0954 (requalified) — DUF5336 domain-containing protein Rv0954 mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG purN (requalified) — phosphoribosylglycinamide formyltransferase purN purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH pimE (requalified) — mannosyltransferase pimE Rv2687c (family_assigned) — fluoroquinolone transporter permease Rv2687c Rv2686c (family_assigned) — fluoroquinolones efflux ABC transporter permease Rv2686c rsmA (requalified) — anti-sigma-M factor RsmA rsmA Rv0210 (family_assigned) — hypothetical protein Rv0210 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv0687 (family_assigned) — Rv0687 family mycofactocin-dependent SDR oxidoredu Rv0687 nirD (family_assigned) — nitrite reductase small subunit NirD nirD rubB (requalified) — rubredoxin RubB rubB rubA (requalified) — rubredoxin rubA Rv1870c (family_assigned) — hypothetical protein Rv1870c Rv1871c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1871c narG (family_assigned) — nitrate reductase subunit alpha narG narX (family_assigned) — respiratory nitrate reductase subunit gamma narX narU (family_assigned) — NarK family nitrate/nitrite MFS transporter narU narK3 (requalified) — nitrate/nitrite transporter narK3 narK1 (requalified) — nitrate/nitrite transporter narK1 purL (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purL hemD (requalified) — uroporphyrin-III C-methyltransferase hemD hemC (requalified) — hydroxymethylbilane synthase hemC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.