MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2595 · 42 genes shown · anchor vapC40 · open gene page → · ← back to 1 hop

Evidence: Min score 0
vapB40 (family_assigned) — AbrB/MazE/SpoVT family DNA-binding domain-containi vapB40 vapC40 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC40 Rv2597 (dark) — DUF4178 domain-containing protein Rv2597 Rv2598 (family_assigned) — DUF2617 family protein Rv2598 ruvA (requalified) — Holliday junction branch migration protein RuvA ruvA ruvC (requalified) — crossover junction endodeoxyribonuclease RuvC ruvC ruvB (requalified) — Holliday junction branch migration DNA helicase Ru ruvB Rv2599 (family_assigned) — DUF4247 domain-containing protein Rv2599 speE (requalified) — spermidine synthase speE vapB27 (requalified) — type II toxin-antitoxin system antitoxin VapB27 vapB27 mazE1 (requalified) — antitoxin MazE1 mazE1 mazE6 (requalified) — antitoxin MazE6 mazE6 mazE9 (requalified) — antitoxin MazE9 mazE9 Rv2600 (family_assigned) — integral membrane protein Rv2600 Rv1006 (family_assigned) — hypothetical protein Rv1006 Rv1868 (family_assigned) — NAD(P)H-binding protein Rv1868 Rv3433c (requalified) — NAD(P)H-hydrate dehydratase Rv3433c Rv2897c (family_assigned) — YifB family Mg chelatase-like AAA ATPase Rv2897c recX (requalified) — recombination regulator RecX recX Rv2898c (family_assigned) — YraN family protein Rv2898c ligA (requalified) — NAD-dependent DNA ligase LigA ligA clpB (requalified) — chaperone protein ClpB clpB polA (requalified) — DNA polymerase I polA Rv0535 (requalified) — 5'-methylthioadenosine phosphorylase Rv0535 mtn (requalified) — 5'-methylthioadenosine/adenosylhomocysteine nucleo mtn vapC27 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC27 Rv0600c (requalified) — two component sensor kinase HK1 Rv0600c Rv0597c (family_assigned) — ATP-binding protein Rv0597c Rv0601c (requalified) — two component sensor kinase HK2 Rv0601c vapC29 (requalified) — type II toxin-antitoxin system ribonuclease VapC29 vapC29 mazF1 (requalified) — toxin MazF1 mazF1 Rv0457c (family_assigned) — prolyl oligopeptidase family protein Rv0457c Rv0459 (family_assigned) — DUF779 domain-containing protein Rv0459 Rv0458 (family_assigned) — aldehyde dehydrogenase family protein Rv0458 echA2 (family_assigned) — crotonase/enoyl-CoA hydratase family protein echA2 mazF9 (requalified) — type II toxin-antitoxin system toxin endoribonucle mazF9 mazF6 (requalified) — type II toxin-antitoxin system toxin endoribonucle mazF6 mazF7 (requalified) — mRNA interferase MazF7 mazF7 mazF3 (requalified) — type II toxin-antitoxin system toxin endoribonucle mazF3 mazF2 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF2 mazF5 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF5 parE1 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to parE1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.