Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2580c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
hisS (requalified) — histidine--tRNA ligase hisS Rv2581c (requalified) — MBL fold metallo-hydrolase Rv2581c aspS (requalified) — aspartate--tRNA ligase aspS hisG (requalified) — ATP phosphoribosyltransferase hisG valS (requalified) — valine--tRNA ligase valS gcpE (requalified) — flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-e gcpE ppiB (requalified) — peptidyl-prolyl cis-trans isomerase B ppiB alaS (requalified) — alanine--tRNA ligase alaS thrS (requalified) — threonine--tRNA ligase thrS guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA manB (requalified) — D-alpha-D-mannose-1-phosphate guanylyltransferase manB lysS (requalified) — lysine--tRNA ligase lysS lysX (requalified) — bifunctional lysine--tRNA ligase/phosphatidylglyce lysX Rv0331 (requalified) — FAD/NAD(P)-binding oxidoreductase Rv0331 truA (requalified) — tRNA pseudouridine synthase A truA rsmH (requalified) — 16S rRNA (cytosine(1402)-N(4))-methyltransferase R rsmH Rv2367c (requalified) — endoribonuclease Rv2367c gatB (family_assigned) — Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subun gatB gatC (family_assigned) — Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subun gatC Rv2571c (family_assigned) — aromatic acid exporter family protein Rv2571c hisE (requalified) — phosphoribosyl-ATP pyrophosphatase hisE hisD (requalified) — histidinol dehydrogenase hisD hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI folC (requalified) — bifunctional tetrahydrofolate synthase/dihydrofola folC Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c ileS (requalified) — isoleucine--tRNA ligase ileS ndkA (requalified) — nucleoside-diphosphate kinase ndkA leuS (requalified) — leucine--tRNA ligase leuS lytB2 (requalified) — 4-hydroxy-3-methylbut-2-enyl diphosphate reductase lytB2 ispF (requalified) — 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate syn ispF Rv3382c (requalified) — 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Rv3382c dxr (requalified) — 1-deoxy-D-xylulose-5-phosphate reductoisomerase dxr Rv2867c (family_assigned) — GNAT family N-acetyltransferase Rv2867c rip (requalified) — zinc metalloprotease Rip rip pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 mas (requalified) — mycocerosate synthase mas pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks12 (requalified) — type I polyketide synthase pks12 htpG (requalified) — molecular chaperone HtpG htpG ruvX (requalified) — Holliday junction resolvase RuvX ruvX mltG (requalified) — endolytic transglycosylase MltG mltG Rv1691 (family_assigned) — hypothetical protein Rv1691

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.