MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2553c · 46 genes shown · anchor aroE · open gene page → · ← back to 1 hop

Evidence: Min score 0
mltG (requalified) — endolytic transglycosylase MltG mltG aroE (requalified) — shikimate dehydrogenase aroE alaS (requalified) — alanine--tRNA ligase alaS ruvX (requalified) — Holliday junction resolvase RuvX ruvX Rv2551c (family_assigned) — A24 family peptidase Rv2551c Rv2556c (requalified) — secondary thiamine-phosphate synthase enzyme YjbQ Rv2556c eccE5 (family_assigned) — type VII secretion system ESX-5 subunit EccE5 eccE5 eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 era (requalified) — GTPase Era era mshD (requalified) — mycothiol synthase mshD mmpL7 (requalified) — phthiocerol dimycocerosate RND transporter MmpL7 mmpL7 Rv3092c (family_assigned) — DUF808 domain-containing protein Rv3092c Rv2851c (family_assigned) — GNAT family N-acetyltransferase Rv2851c aroA (requalified) — 3-phosphoshikimate 1-carboxyvinyltransferase aroA aroB (requalified) — 3-dehydroquinate synthase aroB aroK (requalified) — shikimate kinase AroK aroK aroD (requalified) — type II 3-dehydroquinate dehydratase aroD Rv1691 (family_assigned) — hypothetical protein Rv1691 Rv3529c (requalified) — TLR2-mediated response inhibitor Rv3529c Rv2267c (requalified) — sulfotransferase Rv2267c Rv0038 (family_assigned) — YqgE/AlgH family protein Rv0038 dprA (requalified) — DNA-processing protein DprA dprA Rv2557 (family_assigned) — hypothetical protein Rv2557 mycP5 (requalified) — type VII secretion system ESX-5 serine protease my mycP5 eccD5 (family_assigned) — type VII secretion system ESX-5 subunit EccD5 eccD5 eccA5 (family_assigned) — type VII secretion system ESX-5 AAA family ATPase eccA5 ubiA (requalified) — decaprenyl-phosphate phosphoribosyltransferase ubiA Rv0176 (family_assigned) — RDD family protein Rv0176 eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 eccA1 (family_assigned) — type VII secretion system ESX-1 AAA family ATPase eccA1 eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 esxA (requalified) — ESAT-6 protein EsxA esxA espF (requalified) — type VII secretion system ESX-1 associated protein espF Rv2365c (requalified) — cytidine deaminase Rv2365c Rv2367c (requalified) — endoribonuclease Rv2367c Rv2366c (family_assigned) — hemolysin family protein Rv2366c rpsF (requalified) — 30S ribosomal protein S6 rpsF phoH1 (requalified) — phosphate starvation-inducible protein PhoH phoH1 rpsP (requalified) — 30S ribosomal protein S16 rpsP Rv0818 (requalified) — response regulator transcription factor Rv0818 ppk1 (requalified) — RNA degradosome polyphosphate kinase ppk1 Rv2466c (family_assigned) — Rv2466c family mycothiol-dependent reductase Rv2466c mshC (requalified) — cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D mshC Rv1998c (family_assigned) — isocitrate lyase/phosphoenolpyruvate mutase family Rv1998c mca (requalified) — mycothiol conjugate amidase Mca mca

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.