Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2545 · 45 genes shown · anchor vapC18 · open gene page → · ← back to 1 hop

Evidence: Min score 0
vapB18 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB18 vapC18 (family_assigned) — PIN domain nuclease vapC18 lppB (family_assigned) — LppA family lipoprotein lppB lppA (family_assigned) — LppA family lipoprotein lppA vapC19 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC19 vapB19 (family_assigned) — CopG family transcriptional regulator vapB19 Rv2542 (family_assigned) — alpha/beta hydrolase family protein Rv2542 vapC2 (family_assigned) — PIN domain nuclease vapC2 vapC32 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC32 vapC9 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC9 vapB44 (family_assigned) — CopG family transcriptional regulator vapB44 mazE5 (requalified) — type II toxin-antitoxin system antitoxin MazE5 mazE5 vapB38 (requalified) — antitoxin vapB38 vapC26 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC26 vapC25 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC25 vapC31 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC31 Rv3098A (family_assigned) — PemK-like protein Rv3098A eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 eccE1 (family_assigned) — type VII secretion system ESX-1 subunit EccE1 eccE1 espK (family_assigned) — ESX-1 secretion-associated protein EspK espK eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 esxA (requalified) — ESAT-6 protein EsxA esxA eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 vapB2 (requalified) — type II toxin-antitoxin system antitoxin VapB2 vapB2 Rv0299 (requalified) — toxin-antitoxin system toxin Rv0299 Rv0298 (family_assigned) — ribbon-helix-helix protein%2C CopG family Rv0298 Rv0302 (family_assigned) — TetR/AcrR family transcriptional regulator Rv0302 Rv0303 (requalified) — protochlorophyllide reductase Rv0303 PE_PGRS5 (family_assigned) — PE-PGRS family protein PE_PGRS5 PE_PGRS5 vapB32 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB32 ychF (requalified) — redox-regulated ATPase YchF ychF Rv1115 (family_assigned) — hypothetical protein Rv1115 Rv1111c (family_assigned) — DUF6542 domain-containing protein Rv1111c vapC38 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC38 vapB9 (requalified) — antitoxin VapB9 vapB9 vapC3 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC3 Rv0959 (family_assigned) — VWA domain-containing protein Rv0959 Rv0958 (family_assigned) — ATP-binding protein Rv0958 vapC46 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC46 vapC44 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC44 moaX (requalified) — MoaD-MoaE fusion protein MoaX moaX Rv3322c (requalified) — methyltransferase Rv3322c moaC3 (requalified) — cyclic pyranopterin monophosphate synthase MoaC moaC3 mazF5 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF5 Rv1944c (family_assigned) — SEC-C domain-containing protein Rv1944c

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.