MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2541 · 42 genes shown · anchor aroF · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2541 (dark) — hypothetical protein Rv2541 aroF (requalified) — chorismate synthase aroF aroK (requalified) — shikimate kinase AroK aroK aroB (requalified) — 3-dehydroquinate synthase aroB aroD (requalified) — type II 3-dehydroquinate dehydratase aroD Rv2542 (family_assigned) — alpha/beta hydrolase family protein Rv2542 Rv3224 (requalified) — NAD(P)-dependent oxidoreductase Rv3224 Rv0991c (family_assigned) — FmdB family zinc ribbon protein Rv0991c Rv3729 (requalified) — transferase Rv3729 Rv2012 (family_assigned) — hypothetical protein Rv2012 aroA (requalified) — 3-phosphoshikimate 1-carboxyvinyltransferase aroA Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c Rv0948c (requalified) — chorismate mutase Rv0948c Rv1885c (requalified) — chorismate mutase Rv1885c aroE (requalified) — shikimate dehydrogenase aroE mltG (requalified) — endolytic transglycosylase MltG mltG aroG (requalified) — 3-deoxy-7-phosphoheptulonate synthase class II aroG mbtI (requalified) — salicylate synthase mbtI entC (requalified) — isochorismate synthase entC eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 eccE1 (family_assigned) — type VII secretion system ESX-1 subunit EccE1 eccE1 espK (family_assigned) — ESX-1 secretion-associated protein EspK espK eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 esxA (requalified) — ESAT-6 protein EsxA esxA eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 Rv3224B (family_assigned) — Conserved hypothetical protein Rv3224B Rv3224A (family_assigned) — Conserved hypothetical protein Rv3224A fas (requalified) — fatty acid synthase fas fadE25 (requalified) — acyl-CoA dehydrogenase fadE25 Rv0227c (family_assigned) — membrane protein Rv0227c sigH (family_assigned) — sigma-70 family RNA polymerase sigma factor SigH sigH Rv0992c (requalified) — 5-formyltetrahydrofolate cyclo-ligase Rv0992c galU (requalified) — UTP--glucose-1-phosphate uridylyltransferase galU Rv0990c (family_assigned) — SAF domain-containing protein Rv0990c moeA1 (requalified) — molybdopterin molybdenumtransferase 1 moeA1 rimJ (requalified) — ribosomal-protein-alanine acetyltransferase RimJ rimJ grcC2 (requalified) — polyprenyl-diphosphate synthase GrcC grcC2 Rv3728 (requalified) — MFS transporter Rv3728 Rv3727 (requalified) — FAD-dependent oxidoreductase Rv3727 Rv0213c (requalified) — methyltransferase Rv0213c pheT (family_assigned) — phenylalanine--tRNA ligase subunit beta pheT Rv2011c (family_assigned) — MarR family winged helix-turn-helix transcriptiona Rv2011c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.