Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2528c · 45 genes shown · anchor vapC38 · open gene page → · ← back to 1 hop

Evidence: Min score 0
mrr (requalified) — restriction endonuclease mrr hsdM (requalified) — class I SAM-dependent DNA methyltransferase hsdM Rv2529 (family_assigned) — hypothetical protein Rv2529 vapC38 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC38 hsdS (family_assigned) — restriction endonuclease subunit S hsdS Rv1048c (dark) — hypothetical protein Rv1048c vapC17 (family_assigned) — PIN domain-containing protein vapC17 galK (requalified) — galactokinase galK Rv0325 (family_assigned) — hypothetical protein Rv0325 Rv1833c (requalified) — haloalkane dehalogenase Rv1833c Rv0326 (family_assigned) — hypothetical protein Rv0326 Rv1531 (family_assigned) — carboxymuconolactone decarboxylase family protein Rv1531 vapC21 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC21 thyX (requalified) — FAD-dependent thymidylate synthase thyX Rv2762c (family_assigned) — winged helix-turn-helix domain-containing protein Rv2762c dapA (requalified) — 4-hydroxy-tetrahydrodipicolinate synthase dapA topA (requalified) — type I DNA topoisomerase topA polA (requalified) — DNA polymerase I polA lprE (family_assigned) — LppP/LprE family lipoprotein lprE Rv2090 (requalified) — 5'-3' exonuclease Rv2090 rplA (requalified) — 50S ribosomal protein L1 rplA recA (requalified) — intein-containing recombinase RecA recA vapB38 (requalified) — antitoxin vapB38 Rv2492 (requalified) — hypothetical protein Rv2492 Rv2491 (family_assigned) — TIGR00725 family protein Rv2491 Rv2018 (family_assigned) — DUF433 domain-containing protein Rv2018 vapC32 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC32 vapC13 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC13 vapB42 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB42 vapC42 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC42 Rv1049 (requalified) — oxidation-sensing regulator MosR Rv1049 Rv3833 (family_assigned) — helix-turn-helix transcriptional regulator Rv3833 cyp135A1 (requalified) — cytochrome P450 cyp135A1 Rv0213c (requalified) — methyltransferase Rv0213c vapB17 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB17 vapB2 (requalified) — type II toxin-antitoxin system antitoxin VapB2 vapB2 vapB41 (requalified) — antitoxin VapB41 vapB41 vapB14 (requalified) — antitoxin vapB14 glmS (requalified) — glutamine--fructose-6-phosphate transaminase (isom glmS vapC20 (requalified) — type II toxin-antitoxin system toxin 23S rRNA-spec vapC20 galTa (family_assigned) — Probable galactose-1-phosphate uridylyltransferase galTa galTb (family_assigned) — Probable galactose-1-phosphate uridylyltransferase galTb Rv1752 (family_assigned) — hypothetical protein Rv1752 Rv0648 (requalified) — alpha-mannosidase Rv0648 Rv0745 (family_assigned) — hypothetical protein Rv0745

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.