MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2523c · 46 genes shown · anchor fas · open gene page → · ← back to 1 hop

Evidence: Min score 0
acpS (requalified) — holo-ACP synthase acpS coaE (requalified) — dephospho-CoA kinase coaE fas (requalified) — fatty acid synthase fas Rv2522c (requalified) — dipeptidase Rv2522c mas (requalified) — mycocerosate synthase mas Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks1 (requalified) — polyketide synthase pks1 pks13 (requalified) — polyketide synthase Pks13 pks13 mbtE (requalified) — peptide synthetase mbtE kdtB (requalified) — pantetheine-phosphate adenylyltransferase kdtB rpsA (requalified) — 30S ribosomal protein S1 rpsA polA (requalified) — DNA polymerase I polA Rv1870c (family_assigned) — hypothetical protein Rv1870c rnhB (requalified) — ribonuclease HII rnhB pks7 (requalified) — type I polyketide synthase pks7 pks17 (requalified) — polyketide synthase pks17 accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 pks6 (requalified) — membrane bound polyketide synthase pks6 argC (requalified) — N-acetyl-gamma-glutamyl-phosphate reductase argC argG (requalified) — argininosuccinate synthase argG glmS (requalified) — glutamine--fructose-6-phosphate transaminase (isom glmS nadE (requalified) — NAD(+) synthase nadE fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB Rv1354c (requalified) — bifunctional diguanylate cyclase/phosphodiesterase Rv1354c fbiC (requalified) — bifunctional FO biosynthesis protein CofGH fbiC rsfA (requalified) — anti-sigma-F factor antagonist RsfA rsfA rsfB (family_assigned) — STAS domain-containing protein rsfB Rv1904 (requalified) — anti-sigma factor antagonist Rv1904 Rv2638 (requalified) — anti-sigma factor antagonist Rv2638 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB papA1 (requalified) — acyltransferase PapA1 papA1 pks15 (requalified) — polyketide synthase pks15 mbtC (requalified) — polyketide synthetase MbtC mbtC mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.