MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2499c · 43 genes shown · anchor citE · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2499c (family_assigned) — MaoC family dehydratase Rv2499c citE (family_assigned) — citrate (pro-3S)-lyase subunit beta citE fadE19 (family_assigned) — acyl-CoA dehydrogenase family protein fadE19 accD1 (family_assigned) — acetyl-/propionyl-CoA carboxylase subunit beta accD1 accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 scoB (family_assigned) — succinyl-CoA--3-ketoacid CoA transferase subunit B scoB scoA (family_assigned) — succinyl-CoA--3-ketoacid CoA transferase subunit A scoA Rv2506 (family_assigned) — TetR/AcrR family transcriptional regulator Rv2506 bkdC (family_assigned) — dihydrolipoamide acetyltransferase family protein bkdC bkdA (family_assigned) — pyruvate dehydrogenase (acetyl-transferring) E1 co bkdA bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB icd1 (requalified) — NADP-dependent isocitrate dehydrogenase icd1 fadD35 (family_assigned) — AMP-binding protein fadD35 Rv3075c (requalified) — CoA ester lyase Rv3075c fixB (family_assigned) — electron transfer flavoprotein subunit alpha/FixB fixB fadB (requalified) — fatty oxidation protein FadB fadB fadE13 (family_assigned) — acyl-CoA dehydrogenase family protein fadE13 accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 accD5 (family_assigned) — acyl-CoA carboxylase subunit beta accD5 accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 fas (requalified) — fatty acid synthase fas Rv3551 (family_assigned) — CoA transferase subunit A Rv3551 fadA6 (requalified) — acetyl-CoA C-acetyltransferase fadA6 fadA4 (requalified) — acetyl-CoA acetyltransferase fadA4 iniR (family_assigned) — isoniazid response ATPase/transcriptional regulato iniR Rv3055 (family_assigned) — helix-turn-helix domain-containing protein Rv3055 lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC aceE (requalified) — pyruvate dehydrogenase E1 component aceE Rv0843 (family_assigned) — thiamine pyrophosphate-dependent dehydrogenase E1 Rv0843 dlaT (requalified) — 2-oxoglutarate dehydrogenase%2C E2 component%2C di dlaT Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c mez (requalified) — NAD-dependent malic enzyme mez acn (requalified) — iron-regulated aconitate hydratase Acn acn icd2 (requalified) — NADP-dependent isocitrate dehydrogenase icd2 Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c Rv2454c (family_assigned) — 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2454c mdh (requalified) — malate dehydrogenase mdh rplF (requalified) — 50S ribosomal protein L6 rplF ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks12 (requalified) — type I polyketide synthase pks12 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mas (requalified) — mycocerosate synthase mas

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.