MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2497c · 40 genes shown · anchor bkdC · open gene page → · ← back to 1 hop

Evidence: Min score 0
bkdA (family_assigned) — pyruvate dehydrogenase (acetyl-transferring) E1 co bkdA bkdC (family_assigned) — dihydrolipoamide acetyltransferase family protein bkdC bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC dlaT (requalified) — 2-oxoglutarate dehydrogenase%2C E2 component%2C di dlaT Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c mez (requalified) — NAD-dependent malic enzyme mez Rv1734c (family_assigned) — hypothetical protein Rv1734c pykA (requalified) — pyruvate kinase pykA pca (requalified) — pyruvate carboxylase pca Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c aceE (requalified) — pyruvate dehydrogenase E1 component aceE ppdK (requalified) — pyruvate%2C phosphate dikinase ppdK Rv0843 (family_assigned) — thiamine pyrophosphate-dependent dehydrogenase E1 Rv0843 accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 gcvH (requalified) — glycine cleavage system protein GcvH gcvH sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC Rv0794c (requalified) — oxidoreductase Rv0794c garA (requalified) — glycogen accumulation regulator GarA garA sthA (requalified) — Si-specific NAD(P)(+) transhydrogenase sthA mtr (requalified) — mycothione reductase mtr lpdA (requalified) — NAD(P)H-quinone dehydrogenase lpdA mdh (requalified) — malate dehydrogenase mdh fum (requalified) — class II fumarate hydratase fum glcB (requalified) — malate synthase G glcB eno (requalified) — phosphopyruvate hydratase eno rplJ (requalified) — 50S ribosomal protein L10 rplJ rplX (requalified) — 50S ribosomal protein L24 rplX rplB (requalified) — 50S ribosomal protein L2 rplB rplE (requalified) — 50S ribosomal protein L5 rplE rplF (requalified) — 50S ribosomal protein L6 rplF prpC (requalified) — 2-methylcitrate synthase prpC gltA2 (requalified) — citrate synthase gltA2 citA (requalified) — citrate synthase 2 citA Rv2454c (family_assigned) — 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2454c icd2 (requalified) — NADP-dependent isocitrate dehydrogenase icd2 aroF (requalified) — chorismate synthase aroF pta (requalified) — phosphate acetyltransferase pta sucD (family_assigned) — succinyl-CoA ligase subunit alpha sucD Rv1126c (family_assigned) — MarR family transcriptional regulator Rv1126c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.