MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2443 · 43 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
dctA (family_assigned) — cation:dicarboxylase symporter family transporter dctA sdhD (family_assigned) — succinate dehydrogenase hydrophobic membrane ancho sdhD metH (requalified) — methionine synthase metH Rv1488 (family_assigned) — SPFH domain-containing protein Rv1488 Rv3090 (family_assigned) — SPFH domain-containing protein Rv3090 cstA (family_assigned) — carbon starvation CstA family protein cstA Rv1770 (family_assigned) — hypothetical protein Rv1770 lpqL (family_assigned) — M28 family metallopeptidase lpqL dnaK (requalified) — molecular chaperone DnaK dnaK Rv0312 (family_assigned) — Hsp70 family protein Rv0312 Rv2264c (family_assigned) — Hsp70 family protein Rv2264c Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c sdhB (family_assigned) — succinate dehydrogenase iron-sulfur subunit sdhB sdhA (family_assigned) — succinate dehydrogenase flavoprotein subunit sdhA sdhC (family_assigned) — succinate dehydrogenase%2C cytochrome b556 subunit sdhC frdB (family_assigned) — succinate dehydrogenase iron-sulfur subunit frdB frdA (family_assigned) — fumarate reductase (quinol) flavoprotein subunit frdA Rv0247c (family_assigned) — succinate dehydrogenase/fumarate reductase iron-su Rv0247c Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c metB (requalified) — cystathionine gamma-synthase metB metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC sahH (requalified) — adenosylhomocysteinase sahH Rv1487 (family_assigned) — NfeD family protein Rv1487 ftsH (requalified) — ATP-dependent zinc metalloprotease FtsH ftsH Rv1489 (family_assigned) — hypothetical protein Rv1489 Rv0038 (family_assigned) — YqgE/AlgH family protein Rv0038 mpa (requalified) — proteasome ATPase mpa lytB2 (requalified) — 4-hydroxy-3-methylbut-2-enyl diphosphate reductase lytB2 pepR (family_assigned) — pitrilysin family protein pepR Rv3091 (family_assigned) — patatin-like phospholipase family protein Rv3091 Rv0110 (family_assigned) — integral membrane protein Rv0110 Rv1337 (family_assigned) — rhomboid family intramembrane serine protease Rv1337 ligB (requalified) — ATP-dependent DNA ligase ligB acs (requalified) — acetate--CoA ligase acs Rv1188 (requalified) — proline dehydrogenase Rv1188 fadE22 (requalified) — acyl-CoA dehydrogenase fadE22 Rv1249c (family_assigned) — hypothetical protein Rv1249c Rv1769 (requalified) — amino acid deaminase/aldolase Rv1769 Rv1771 (requalified) — L-gulono-1%2C4-lactone dehydrogenase Rv1771 lipT (requalified) — carboxylesterase LipT lipT

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.