MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2376c · 46 genes shown · anchor mbtG · open gene page → · ← back to 1 hop

Evidence: Min score 0
cfp2 (requalified) — Low molecular weight antigen MTB12 cfp2 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG mbtF (requalified) — peptide synthetase mbtF mbtE (requalified) — peptide synthetase mbtE mpt64 (requalified) — immunoprotective protein Mpt64 mpt64 rpsO (requalified) — 30S ribosomal protein S15 rpsO Rv1639c (family_assigned) — alpha/beta hydrolase family protein Rv1639c esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB cfp6 (requalified) — low molecular weight protein antigen 6 cfp6 aroD (requalified) — type II 3-dehydroquinate dehydratase aroD gcp (family_assigned) — tRNA (adenosine(37)-N6)-threonylcarbamoyltransfera gcp PE31 (family_assigned) — PE family protein PE31 PE31 pks13 (requalified) — polyketide synthase Pks13 pks13 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtC (requalified) — polyketide synthetase MbtC mbtC fas (requalified) — fatty acid synthase fas Rv1979c (family_assigned) — APC family permease Rv1979c nrdF1 (family_assigned) — ribonucleoside-diphosphate reductase subunit beta nrdF1 fbpA (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpA pstS1 (family_assigned) — phosphate ABC transporter substrate-binding lipopr pstS1 rpoB (family_assigned) — DNA-directed RNA polymerase subunit beta rpoB lppX (requalified) — LppX_LprAFG lipoprotein lppX rplR (requalified) — 50S ribosomal protein L18 rplR rpmA (requalified) — 50S ribosomal protein L27 rpmA rpmE (requalified) — 50S ribosomal protein L31 rpmE rplY (requalified) — 50S ribosomal protein L25/general stress protein C rplY rpmG2 (requalified) — 50S ribosomal protein L33 rpmG2 rplU (requalified) — 50S ribosomal protein L21 rplU Rv1638A (family_assigned) — hypothetical protein Rv1638A mftF (requalified) — mycofactocin biosynthesis glycosyltransferase MftF mftF Rv2160A (family_assigned) — Conserved hypothetical protein Rv2160A mftE (requalified) — mycofactocin biosynthesis peptidyl-dipeptidase Mft mftE lysX (requalified) — bifunctional lysine--tRNA ligase/phosphatidylglyce lysX Rv3479 (requalified) — transmembrane protein Rv3479 esxA (requalified) — ESAT-6 protein EsxA esxA eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 esxJ (requalified) — type VII secretion system ESX-5 protein EsxJ esxJ esxL (requalified) — type VII secretion system ESX-5 protein EsxL esxL esxW (requalified) — type VII secretion system protein EsxW esxW Rv2520c (dark) — DUF3618 domain-containing protein Rv2520c Rv1109c (requalified) — lipid droplet-associated protein Rv1109c Rv3311 (family_assigned) — primosomal protein Rv3311

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.