MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2274c · 46 genes shown · anchor mazE8 · open gene page → · ← back to 1 hop

Evidence: Min score 0
mazF8 (requalified) — toxin mazF8 mazE8 (requalified) — antitoxin MazE8 mazE8 Rv2275 (requalified) — cyclo(L-tyrosyl-L-tyrosyl) synthase Rv2275 cyp121 (requalified) — mycocyclosin synthase Cyp121 cyp121 vapC6 (requalified) — ribonuclease VapC6 vapC6 vapC12 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC12 vapC10 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC10 esxF (requalified) — pore-forming CpnT exporter EsxF esxF lppL (family_assigned) — hypothetical protein lppL Rv1004c (family_assigned) — hypothetical protein Rv1004c vapB42 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB42 Rv3289c (dark) — hypothetical protein Rv3289c Rv0996 (family_assigned) — hypothetical protein Rv0996 mazE2 (family_assigned) — ribbon-helix-helix protein%2C CopG family mazE2 mazE3 (requalified) — antitoxin MazE3 mazE3 mazE1 (requalified) — antitoxin MazE1 mazE1 PE_PGRS28 (family_assigned) — PE-PGRS family protein PE_PGRS28 PE_PGRS28 PE_PGRS43 (family_assigned) — PE-PGRS family protein PE_PGRS43 PE_PGRS43 PPE8 (family_assigned) — PPE family protein PPE8 PPE8 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 PPE55 (family_assigned) — PPE family protein PPE55 PPE55 pks13 (requalified) — polyketide synthase Pks13 pks13 Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 mbtE (requalified) — peptide synthetase mbtE Rv2776c (requalified) — oxidoreductase Rv2776c rplF (requalified) — 50S ribosomal protein L6 rplF vapB6 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB6 vapB2 (requalified) — type II toxin-antitoxin system antitoxin VapB2 vapB2 Rv0658c (family_assigned) — CPBP family intramembrane glutamic endopeptidase Rv0658c vapB41 (requalified) — antitoxin VapB41 vapB41 vapB14 (requalified) — antitoxin vapB14 vapB12 (requalified) — antitoxin vapB12 Rv3098A (family_assigned) — PemK-like protein Rv3098A vapC46 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC46 vapC35 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC35 vapB47 (requalified) — antitoxin VapB47 vapB47 mazE9 (requalified) — antitoxin MazE9 mazE9 vapB10 (family_assigned) — CopG family transcriptional regulator vapB10 nlhH (family_assigned) — alpha/beta hydrolase nlhH lipI (family_assigned) — alpha/beta hydrolase lipI Rv0611c (family_assigned) — DUF4926 domain-containing protein Rv0611c vapC20 (requalified) — type II toxin-antitoxin system toxin 23S rRNA-spec vapC20 PE_PGRS25 (family_assigned) — PE-PGRS family protein PE_PGRS25 PE_PGRS25 esxE (requalified) — ESAT-6 like protein EsxE esxE cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT ift (requalified) — necrotizing toxin immunity factor IFT ift

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.