MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2274A · 45 genes shown · anchor mazF8 · open gene page → · ← back to 1 hop

Evidence: Min score 0
mazE8 (requalified) — antitoxin MazE8 mazE8 mazF8 (requalified) — toxin mazF8 cyp121 (requalified) — mycocyclosin synthase Cyp121 cyp121 Rv2275 (requalified) — cyclo(L-tyrosyl-L-tyrosyl) synthase Rv2275 mazE2 (family_assigned) — ribbon-helix-helix protein%2C CopG family mazE2 mazE3 (requalified) — antitoxin MazE3 mazE3 mazE1 (requalified) — antitoxin MazE1 mazE1 vapB42 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB42 mazE6 (requalified) — antitoxin MazE6 mazE6 mazF6 (requalified) — type II toxin-antitoxin system toxin endoribonucle mazF6 vapC46 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC46 vapC6 (requalified) — ribonuclease VapC6 vapC6 vapC12 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC12 vapC10 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC10 pks13 (requalified) — polyketide synthase Pks13 pks13 Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 mbtE (requalified) — peptide synthetase mbtE Rv2776c (requalified) — oxidoreductase Rv2776c rplF (requalified) — 50S ribosomal protein L6 rplF PE_PGRS28 (family_assigned) — PE-PGRS family protein PE_PGRS28 PE_PGRS28 PE_PGRS43 (family_assigned) — PE-PGRS family protein PE_PGRS43 PE_PGRS43 PPE8 (family_assigned) — PPE family protein PPE8 PPE8 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 PPE55 (family_assigned) — PPE family protein PPE55 PPE55 mazF2 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF2 vapB7 (requalified) — antitoxin vapB7 vapC7 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC7 Rv0658c (family_assigned) — CPBP family intramembrane glutamic endopeptidase Rv0658c mazF3 (requalified) — type II toxin-antitoxin system toxin endoribonucle mazF3 parE1 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to parE1 Rv1101c (family_assigned) — AI-2E family transporter Rv1101c mazF7 (requalified) — mRNA interferase MazF7 mazF7 mazF1 (requalified) — toxin MazF1 mazF1 Rv0457c (family_assigned) — prolyl oligopeptidase family protein Rv0457c Rv0459 (family_assigned) — DUF779 domain-containing protein Rv0459 Rv0458 (family_assigned) — aldehyde dehydrogenase family protein Rv0458 echA2 (family_assigned) — crotonase/enoyl-CoA hydratase family protein echA2 mazF9 (requalified) — type II toxin-antitoxin system toxin endoribonucle mazF9 vapC42 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC42 hsdS (family_assigned) — restriction endonuclease subunit S hsdS Rv2762c (family_assigned) — winged helix-turn-helix domain-containing protein Rv2762c Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ Rv3488 (family_assigned) — PadR family transcriptional regulator Rv3488 mazE9 (requalified) — antitoxin MazE9 mazE9

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.