MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2270 · 46 genes shown · anchor cyp128 · open gene page → · ← back to 1 hop

Evidence: Min score 0
lppN (family_assigned) — hypothetical protein lppN Rv2271 (dark) — DUF2695 domain-containing protein Rv2271 Rv2269c (family_assigned) — hypothetical protein Rv2269c cyp128 (requalified) — cytochrome P450 cyp128 Rv2267c (requalified) — sulfotransferase Rv2267c Rv2272 (family_assigned) — YidH family protein Rv2272 Rv2273 (dark) — DUF202 domain-containing protein Rv2273 mce3C (family_assigned) — virulence factor Mce family protein mce3C lprM (family_assigned) — Mce family lipoprotein LprM lprM Rv1973 (family_assigned) — hypothetical protein Rv1973 Rv1351 (dark) — hypothetical protein Rv1351 lppD (requalified) — lipoprotein LppD lppD lppC (family_assigned) — YbhB/YbcL family Raf kinase inhibitor-like protein lppC cyp124 (requalified) — methyl-branched lipid omega-hydroxylase Cyp124 cyp124 pks13 (requalified) — polyketide synthase Pks13 pks13 Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 mbtE (requalified) — peptide synthetase mbtE Rv2776c (requalified) — oxidoreductase Rv2776c htpG (requalified) — molecular chaperone HtpG htpG alaS (requalified) — alanine--tRNA ligase alaS rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA mftF (requalified) — mycofactocin biosynthesis glycosyltransferase MftF mftF rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ Rv3066 (family_assigned) — TetR/AcrR family transcriptional regulator Rv3066 Rv2779c (family_assigned) — Lrp/AsnC family transcriptional regulator Rv2779c Rv3777 (requalified) — oxidoreductase Rv3777 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD yrbE3A (family_assigned) — ABC transporter permease yrbE3A yrbE3B (family_assigned) — ABC transporter permease yrbE3B mce3A (family_assigned) — Mce family protein Mce3A mce3A Rv1972 (requalified) — Mce associated membrane protein Rv1972 mce3F (family_assigned) — MlaD family protein mce3F mce3B (family_assigned) — virulence factor Mce family protein mce3B Rv1975 (family_assigned) — CAP domain-containing protein Rv1975 fabG2 (requalified) — 3-oxoacyl-ACP reductase FabG fabG2 irtB (family_assigned) — iron ABC transporter ATP-binding protein/permease irtB irtA (family_assigned) — iron ABC transporter ATP-binding protein/permease irtA Rv1352 (family_assigned) — hypothetical protein Rv1352 arfA (family_assigned) — peptidoglycan-binding protein ArfA arfA lipJ (family_assigned) — adenylate/guanylate cyclase domain-containing prot lipJ cobB (requalified) — NAD-dependent protein deacylase cobB cinA (requalified) — competence/damage-inducible protein A cinA Rv2972c (family_assigned) — HNH endonuclease family protein Rv2972c Rv0143c (requalified) — chloride channel protein Rv0143c Rv3433c (requalified) — NAD(P)H-hydrate dehydratase Rv3433c rplP (requalified) — 50S ribosomal protein L16 rplP

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.