MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2225 · 46 genes shown · anchor panC · open gene page → · ← back to 1 hop

Evidence: Min score 0
panB (requalified) — 3-methyl-2-oxobutanoate hydroxymethyltransferase panB panC (requalified) — pantoate--beta-alanine ligase panC panD (requalified) — aspartate 1-decarboxylase panD Rv2573 (requalified) — 2-dehydropantoate 2-reductase Rv2573 ilvE (requalified) — branched-chain amino acid aminotransferase ilvE ilvD (requalified) — dihydroxy-acid dehydratase ilvD Rv2226 (family_assigned) — CYTH and CHAD domain-containing protein Rv2226 Rv3603c (family_assigned) — Rossmann-like and DUF2520 domain-containing protei Rv3603c gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB nadE (requalified) — NAD(+) synthase nadE guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA ribA2 (requalified) — bifunctional 3%2C4-dihydroxy-2-butanone-4-phosphat ribA2 ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1 Rv3600c (requalified) — type III pantothenate kinase Rv3600c gadB (requalified) — glutamate decarboxylase gadB aldA (requalified) — aldehyde dehydrogenase aldA Rv0223c (requalified) — aldehyde dehydrogenase Rv0223c Rv2575 (requalified) — neutral zinc metallopeptidase Rv2575 aspS (requalified) — aspartate--tRNA ligase aspS Rv2574 (family_assigned) — SRPBCC family protein Rv2574 Rv1000c (family_assigned) — hypothetical protein Rv1000c leuA (requalified) — 2-isopropylmalate synthase leuA metB (requalified) — cystathionine gamma-synthase metB aspC (requalified) — pyridoxal phosphate-dependent aminotransferase aspC gshA (requalified) — ergothioneine biosynthesis glutamate--cysteine lig gshA ilvC (requalified) — ketol-acid reductoisomerase ilvC ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 leuC (family_assigned) — 3-isopropylmalate dehydratase large subunit leuC Rv0210 (family_assigned) — hypothetical protein Rv0210 Rv1619 (requalified) — bifunctional lysylphosphatidylglycerol flippase/sy Rv1619 Rv3689 (requalified) — transmembrane protein Rv3689 Rv2025c (family_assigned) — cation diffusion facilitator family transporter Rv2025c Rv1978 (requalified) — class I SAM-dependent methyltransferase Rv1978 lysS (requalified) — lysine--tRNA ligase lysS Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c lsr2 (requalified) — histone-like nucleoid-structuring protein Lsr2 lsr2 gcvH (requalified) — glycine cleavage system protein GcvH gcvH gcvT (requalified) — aminomethyltransferase gcvT glyA1 (requalified) — serine hydroxymethyltransferase glyA1 glyA2 (requalified) — serine hydroxymethyltransferase glyA2 Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c purD (requalified) — phosphoribosylamine--glycine ligase purD nadR (requalified) — nicotinamide-nucleotide adenylyltransferase nadR nadD (requalified) — nicotinate-nucleotide adenylyltransferase nadD cobB (requalified) — NAD-dependent protein deacylase cobB ppnK (requalified) — NAD kinase ppnK

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.