MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2219 · 46 genes shown · anchor lipB · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2219 (family_assigned) — DUF4191 domain-containing protein Rv2219 lipB (requalified) — lipoyl(octanoyl) transferase LipB lipB lipA (requalified) — lipoyl synthase lipA Rv2216 (family_assigned) — TIGR01777 family oxidoreductase Rv2216 dlaT (requalified) — 2-oxoglutarate dehydrogenase%2C E2 component%2C di dlaT Rv2708c (family_assigned) — hypothetical protein Rv2708c Rv1830 (family_assigned) — HTH-type transcriptional regulator Rv1830 rbpA (family_assigned) — RNA polymerase-binding protein RbpA rbpA Rv2413c (family_assigned) — DNA polymerase III subunit delta Rv2413c Rv2680 (dark) — DUF3000 domain-containing protein Rv2680 Rv3195 (requalified) — zinc-dependent metalloprotease Rv3195 Rv1002c (requalified) — dolichyl-phosphate-mannose--protein mannosyltransf Rv1002c Rv2699c (dark) — DUF4193 domain-containing protein Rv2699c gcvH (requalified) — glycine cleavage system protein GcvH gcvH fas (requalified) — fatty acid synthase fas bkdC (family_assigned) — dihydrolipoamide acetyltransferase family protein bkdC arcA (requalified) — arginine deiminase arcA ephD (family_assigned) — SDR family oxidoreductase ephD lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB aceE (requalified) — pyruvate dehydrogenase E1 component aceE sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC bkdA (family_assigned) — pyruvate dehydrogenase (acetyl-transferring) E1 co bkdA Rv2709 (dark) — DUF3099 domain-containing protein Rv2709 Rv2731 (family_assigned) — DUF349 domain-containing protein Rv2731 rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ secG (family_assigned) — preprotein translocase subunit SecG secG whiB2 (family_assigned) — transcriptional regulator WhiB2 whiB2 whiB1 (family_assigned) — transcriptional regulator WhiB1 whiB1 rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA sigA (requalified) — RNA polymerase sigma factor sigA rpoC (family_assigned) — DNA-directed RNA polymerase subunit beta' rpoC rpoB (family_assigned) — DNA-directed RNA polymerase subunit beta rpoB sigB (family_assigned) — sigma-70 family RNA polymerase sigma factor SigB sigB Rv3644c (family_assigned) — DNA polymerase III subunit delta' Rv3644c dnaN (family_assigned) — DNA polymerase III subunit beta dnaN dnaZX (family_assigned) — DNA polymerase III subunits gamma/tau dnaZX dnaE1 (family_assigned) — DNA polymerase III subunit alpha dnaE1 Rv2191 (family_assigned) — hypothetical protein Rv2191 dnaQ (family_assigned) — DEDDh family exonuclease dnaQ Rv2681 (requalified) — ribonuclease D Rv2681 hemQ (requalified) — hydrogen peroxide-dependent heme synthase hemQ echA15 (family_assigned) — enoyl-CoA hydratase/isomerase family protein echA15 Rv2256c (dark) — hypothetical protein Rv2256c Rv3194c (family_assigned) — PDZ domain-containing protein Rv3194c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.