MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2211c · 34 genes shown · anchor gcvH · open gene page → · ← back to 1 hop

Evidence: Min score 0
gcvT (requalified) — aminomethyltransferase gcvT gcvH (requalified) — glycine cleavage system protein GcvH gcvH gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH metH (requalified) — methionine synthase metH purN (requalified) — phosphoribosylglycinamide formyltransferase purN purT (requalified) — phosphoribosylglycinamide formyltransferase 2 purT purU (requalified) — formyltetrahydrofolate deformylase purU fmt (requalified) — methionyl-tRNA formyltransferase fmt Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c purD (requalified) — phosphoribosylamine--glycine ligase purD sdaA (requalified) — L-serine ammonia-lyase sdaA dlaT (requalified) — 2-oxoglutarate dehydrogenase%2C E2 component%2C di dlaT bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB bkdC (family_assigned) — dihydrolipoamide acetyltransferase family protein bkdC bkdA (family_assigned) — pyruvate dehydrogenase (acetyl-transferring) E1 co bkdA purB (requalified) — adenylosuccinate lyase purB purA (requalified) — adenylosuccinate synthase purA Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c metB (requalified) — cystathionine gamma-synthase metB metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC sahH (requalified) — adenosylhomocysteinase sahH purM (requalified) — phosphoribosylformylglycinamidine cyclo-ligase purM purQ (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purQ purL (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purL Rv0787A (family_assigned) — hypothetical protein Rv0787A fmu (requalified) — 16S rRNA m5C967 methyltransferase fmu dfrA (requalified) — dihydrofolate reductase dfrA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.