Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2142c · 27 genes shown · anchor parD2 · open gene page → · ← back to 1 hop

Evidence: Min score 0
parE2 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to parE2 parD2 (requalified) — antitoxin ParD2 parD2 Rv2143 (family_assigned) — phosphoribosyltransferase family protein Rv2143 parE1 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to parE1 parD1 (family_assigned) — type II toxin-antitoxin system ParD family antitox parD1 hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA vapC23 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC23 vapC13 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC13 Rv0574c (family_assigned) — CapA family protein Rv0574c Rv2625c (family_assigned) — site-2 protease family protein Rv2625c dapA (requalified) — 4-hydroxy-tetrahydrodipicolinate synthase dapA Rv2472 (dark) — hypothetical protein Rv2472 mazE9 (requalified) — antitoxin MazE9 mazE9 mazE3 (requalified) — antitoxin MazE3 mazE3 Rv1958c (dark) — hypothetical protein Rv1958c Rv1961 (family_assigned) — hypothetical protein Rv1961 vapC30 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC30 cobB (requalified) — NAD-dependent protein deacylase cobB lrpA (family_assigned) — transcriptional regulator LrpA lrpA Rv3488 (family_assigned) — PadR family transcriptional regulator Rv3488 nadR (requalified) — nicotinamide-nucleotide adenylyltransferase nadR hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB hisD (requalified) — histidinol dehydrogenase hisD hisC1 (requalified) — histidinol-phosphate aminotransferase hisC1

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.