MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2120c · 46 genes shown · anchor hisG · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2120c (family_assigned) — glycine zipper 2TM domain-containing protein Rv2120c hisG (requalified) — ATP phosphoribosyltransferase hisG hisE (requalified) — phosphoribosyl-ATP pyrophosphatase hisE pirG (requalified) — exported repetitive protein pirG Rv3707c (requalified) — hypothetical protein Rv3707c Rv0315 (requalified) — family 16 glycosylhydrolase Rv0315 Rv2743c (family_assigned) — hypothetical protein Rv2743c eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 Rv3096 (requalified) — 1%2C4-beta-xylanase Rv3096 lpqF (requalified) — serine hydrolase lpqF Rv1216c (family_assigned) — isoprenylcysteine carboxylmethyltransferase family Rv1216c PPE37 (family_assigned) — PPE family protein PPE37 PPE37 Rv1856c (family_assigned) — SDR family oxidoreductase Rv1856c hisD (requalified) — histidinol dehydrogenase hisD hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA Rv2721c (family_assigned) — LGFP repeat-containing protein Rv2721c Rv0312 (family_assigned) — Hsp70 family protein Rv0312 fbpC (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpC ripA (family_assigned) — NlpC/P60 family peptidoglycan endopeptidase RipA ripA Rv1158c (dark) — hypothetical protein Rv1158c mtc28 (family_assigned) — LpqN/LpqT family lipoprotein mtc28 ask (requalified) — aspartate kinase ask asd (requalified) — aspartate-semialdehyde dehydrogenase asd Rv0316 (family_assigned) — muconolactone Delta-isomerase family protein Rv0316 Rv0314c (family_assigned) — membrane protein Rv0314c Rv1987 (family_assigned) — cellulose-binding protein Rv1987 35kd_ag (family_assigned) — hypothetical protein 35kd_ag lppL (family_assigned) — hypothetical protein lppL chiZ (requalified) — cell wall hydrolase ChiZ chiZ lmeA (requalified) — mannan chain length control protein LmeA lmeA eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 eccE3 (family_assigned) — type VII secretion system ESX-3 subunit EccE3 eccE3 mycP3 (requalified) — type VII secretion system ESX-3 serine protease my mycP3 espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 Rv3717 (family_assigned) — hypothetical protein Rv3717 Rv3209 (family_assigned) — MmpS family transport accessory protein Rv3209 Rv0063 (requalified) — FAD-binding oxidoreductase Rv0063 Rv3095 (family_assigned) — helix-turn-helix domain-containing protein Rv3095 Rv3094c (family_assigned) — acyl-CoA dehydrogenase family protein Rv3094c mhuD (requalified) — mycobilin-forming heme oxygenase MhuD mhuD

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.