MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1955 · 46 genes shown · anchor higA · open gene page → · ← back to 1 hop

Evidence: Min score 0
higB (requalified) — type II toxin-antitoxin system toxin HigB higB higA (requalified) — type II toxin-antitoxin system antitoxin HigA higA Rv1957 (requalified) — SecB-like chaperone Rv1957 Rv1954A (dark) — Hypothetical protein Rv1954A cbs (requalified) — cystathionine beta-synthase cbs guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 Rv2021c (family_assigned) — XRE family transcriptional regulator Rv2021c Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 vapB14 (requalified) — antitoxin vapB14 Rv1954c (requalified) — hypothetical protein Rv1954c vapC46 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC46 relE (requalified) — type II toxin-antitoxin system mRNA interferase Re relE mazF3 (requalified) — type II toxin-antitoxin system toxin endoribonucle mazF3 PPE55 (family_assigned) — PPE family protein PPE55 PPE55 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 PPE8 (family_assigned) — PPE family protein PPE8 PPE8 Rv0836c (family_assigned) — hypothetical protein Rv0836c rpfE (requalified) — resuscitation-promoting factor protein RpfE rpfE rpfC (requalified) — resuscitation-promoting factor RpfC rpfC rpfD (requalified) — resuscitation-promoting factor protein RpfD rpfD rpfA (requalified) — resuscitation-promoting factor protein RpfA rpfA Rv1861 (family_assigned) — GlsB/YeaQ/YmgE family stress response membrane pro Rv1861 metB (requalified) — cystathionine gamma-synthase metB metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ cysE (requalified) — serine O-acetyltransferase cysE sahH (requalified) — adenosylhomocysteinase sahH glyA1 (requalified) — serine hydroxymethyltransferase glyA1 glyA2 (requalified) — serine hydroxymethyltransferase glyA2 guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA purA (requalified) — adenylosuccinate synthase purA purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH guaB2 (requalified) — IMP dehydrogenase guaB2 rdgB (family_assigned) — RdgB/HAM1 family non-canonical purine NTP pyrophos rdgB guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 Rv2022c (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv2022c Rv3182 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv3182 Rv2023c (dark) — hypothetical protein Rv2023c Rv0744c (family_assigned) — helix-turn-helix domain-containing protein Rv0744c Rv2020c (family_assigned) — Conserved hypothetical protein Rv2020c Rv0332 (family_assigned) — hypothetical protein Rv0332 mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 Rv3066 (family_assigned) — TetR/AcrR family transcriptional regulator Rv3066 Rv3840 (family_assigned) — transcriptional regulator Rv3840 Rv1776c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1776c vapC14 (requalified) — ribonuclease VapC14 vapC14

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.