MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1912c · 46 genes shown · anchor mbtC · open gene page → · ← back to 1 hop

Evidence: Min score 0
fadB5 (family_assigned) — medium chain dehydrogenase/reductase family protei fadB5 mbtC (requalified) — polyketide synthetase MbtC mbtC pks17 (requalified) — polyketide synthase pks17 pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 pks15 (requalified) — polyketide synthase pks15 pks9 (requalified) — type I polyketide synthase pks9 pks6 (requalified) — membrane bound polyketide synthase pks6 Rv1913 (requalified) — MBL fold metallo-hydrolase Rv1913 lppC (family_assigned) — YbhB/YbcL family Raf kinase inhibitor-like protein lppC ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB Rv1910c (family_assigned) — YbhB/YbcL family Raf kinase inhibitor-like protein Rv1910c ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtE (requalified) — peptide synthetase mbtE mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtF (requalified) — peptide synthetase mbtF pks1 (requalified) — polyketide synthase pks1 pks8 (requalified) — polyketide synthase pks8 fas (requalified) — fatty acid synthase fas pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 papA3 (requalified) — acyltransferase PapA3 papA3 Rv3777 (requalified) — oxidoreductase Rv3777 fadB4 (family_assigned) — NADPH:quinone oxidoreductase family protein fadB4 fadD29 (requalified) — long-chain-fatty-acid--AMP ligase FadD29 fadD29 fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c pks7 (requalified) — type I polyketide synthase pks7 fadD30 (requalified) — long-chain-fatty-acid--AMP ligase FadD30 fadD30 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp Rv0331 (requalified) — FAD/NAD(P)-binding oxidoreductase Rv0331 Rv3071 (family_assigned) — DUF190 domain-containing protein Rv3071 echA3 (family_assigned) — crotonase/enoyl-CoA hydratase family protein echA3 Rv1929c (family_assigned) — TIGR03085 family metal-binding protein Rv1929c rplP (requalified) — 50S ribosomal protein L16 rplP rplB (requalified) — 50S ribosomal protein L2 rplB rpsB (requalified) — 30S ribosomal protein S2 rpsB rplM (requalified) — 50S ribosomal protein L13 rplM rpsE (requalified) — 30S ribosomal protein S5 rpsE rpsO (requalified) — 30S ribosomal protein S15 rpsO ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC fadD26 (requalified) — long-chain-fatty-acid--AMP ligase FAAL26/FadD26 fadD26 ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD drrB (family_assigned) — daunorubicin ABC transporter permease DrrB drrB drrA (family_assigned) — daunorubicin ABC transporter ATP-binding protein D drrA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.