MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1872c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
lldD2 (requalified) — quinone-dependent L-lactate dehydrogenase lldD2 Rv1871c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1871c pykA (requalified) — pyruvate kinase pykA mftD (requalified) — pre-mycofactocin synthase MftD mftD pca (requalified) — pyruvate carboxylase pca Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c mez (requalified) — NAD-dependent malic enzyme mez bkdA (family_assigned) — pyruvate dehydrogenase (acetyl-transferring) E1 co bkdA Rv2454c (family_assigned) — 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2454c aceE (requalified) — pyruvate dehydrogenase E1 component aceE bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB ppdK (requalified) — pyruvate%2C phosphate dikinase ppdK ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 fbpA (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpA Rv1870c (family_assigned) — hypothetical protein Rv1870c carD (requalified) — RNA polymerase-binding transcription factor CarD carD tuf (requalified) — elongation factor Tu tuf cspA (requalified) — cold shock protein CspA cspA eno (requalified) — phosphopyruvate hydratase eno rplJ (requalified) — 50S ribosomal protein L10 rplJ rplX (requalified) — 50S ribosomal protein L24 rplX rplB (requalified) — 50S ribosomal protein L2 rplB rplE (requalified) — 50S ribosomal protein L5 rplE rplF (requalified) — 50S ribosomal protein L6 rplF mftC (requalified) — mycofactocin radical SAM maturase mftC mftB (requalified) — mycofactocin biosynthesis chaperone MftB mftB prpC (requalified) — 2-methylcitrate synthase prpC gltA2 (requalified) — citrate synthase gltA2 citA (requalified) — citrate synthase 2 citA mdh (requalified) — malate dehydrogenase mdh icd2 (requalified) — NADP-dependent isocitrate dehydrogenase icd2 aroF (requalified) — chorismate synthase aroF pta (requalified) — phosphate acetyltransferase pta sucD (family_assigned) — succinyl-CoA ligase subunit alpha sucD sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC fum (requalified) — class II fumarate hydratase fum glcB (requalified) — malate synthase G glcB bkdC (family_assigned) — dihydrolipoamide acetyltransferase family protein bkdC lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC dlaT (requalified) — 2-oxoglutarate dehydrogenase%2C E2 component%2C di dlaT Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c mobA (requalified) — molybdenum cofactor guanylyltransferase mobA Rv0843 (family_assigned) — thiamine pyrophosphate-dependent dehydrogenase E1 Rv0843 Rv1126c (family_assigned) — MarR family transcriptional regulator Rv1126c ilvN (family_assigned) — acetolactate synthase small subunit ilvN ilvC (requalified) — ketol-acid reductoisomerase ilvC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.