MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1847 · 43 genes shown · anchor ureA · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1847 (family_assigned) — PaaI family thioesterase Rv1847 menB (requalified) — 1,4-dihydroxy-2-naphthoyl-CoA synthase menB menA (requalified) — 1%2C4-dihydroxy-2-naphthoate polyprenyltransferase menA ureA (family_assigned) — urease subunit gamma ureA ureC (family_assigned) — urease subunit alpha ureC ureF (requalified) — urease accessory protein UreF ureF ureB (family_assigned) — urease subunit beta ureB ureG (requalified) — urease accessory protein UreG ureG ureD (requalified) — urease accessory protein UreD ureD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 fas (requalified) — fatty acid synthase fas blaI (requalified) — transcriptional repressor BlaI blaI menE (requalified) — o-succinylbenzoate--CoA ligase menE menD (requalified) — 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1 menD menC (requalified) — o-succinylbenzoate synthase menC Rv0544c (family_assigned) — hypothetical protein Rv0544c menH (requalified) — demethylmenaquinone methyltransferase menH Rv0535 (requalified) — 5'-methylthioadenosine phosphorylase Rv0535 galE3 (requalified) — UDP-glucose 4-epimerase GalE galE3 hycE (family_assigned) — NADH-quinone oxidoreductase subunit C hycE iniR (family_assigned) — isoniazid response ATPase/transcriptional regulato iniR mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtE (requalified) — peptide synthetase mbtE mbtC (requalified) — polyketide synthetase MbtC mbtC pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA purA (requalified) — adenylosuccinate synthase purA purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH guaB2 (requalified) — IMP dehydrogenase guaB2 rdgB (family_assigned) — RdgB/HAM1 family non-canonical purine NTP pyrophos rdgB guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 pks7 (requalified) — type I polyketide synthase pks7 pks17 (requalified) — polyketide synthase pks17 mas (requalified) — mycocerosate synthase mas accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 pks6 (requalified) — membrane bound polyketide synthase pks6 blaR (family_assigned) — M56 family metallopeptidase blaR gnd1 (requalified) — 6-phosphogluconate dehydrogenase gnd1 Rv1842c (family_assigned) — hemolysin family protein Rv1842c Rv1841c (family_assigned) — hemolysin family protein Rv1841c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.