MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1843c · 37 genes shown · anchor guaA · open gene page → · ← back to 1 hop

Evidence: Min score 0
guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA purA (requalified) — adenylosuccinate synthase purA purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH guaB2 (requalified) — IMP dehydrogenase guaB2 rdgB (family_assigned) — RdgB/HAM1 family non-canonical purine NTP pyrophos rdgB guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 hpt (requalified) — hypoxanthine phosphoribosyltransferase hpt Rv1021 (requalified) — nucleoside triphosphate pyrophosphohydrolase Rv1021 gnd1 (requalified) — 6-phosphogluconate dehydrogenase gnd1 blaI (requalified) — transcriptional repressor BlaI blaI blaR (family_assigned) — M56 family metallopeptidase blaR Rv1842c (family_assigned) — hemolysin family protein Rv1842c apt (requalified) — adenine phosphoribosyltransferase apt argS (requalified) — arginine--tRNA ligase argS rplK (requalified) — 50S ribosomal protein L11 rplK purB (requalified) — adenylosuccinate lyase purB Rv0356c (family_assigned) — PaaI family thioesterase Rv0356c purN (requalified) — phosphoribosylglycinamide formyltransferase purN glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 purT (requalified) — phosphoribosylglycinamide formyltransferase 2 purT rphA (requalified) — ribonuclease PH rphA murI (requalified) — glutamate racemase murI ndkA (requalified) — nucleoside-diphosphate kinase ndkA mesJ (requalified) — tRNA lysidine(34) synthetase TilS mesJ deoD (requalified) — purine-nucleoside phosphorylase deoD devB (requalified) — 6-phosphogluconolactonase devB zwf1 (requalified) — glucose-6-phosphate 1-dehydrogenase zwf1 rpe (requalified) — ribulose-phosphate 3-epimerase rpe zwf2 (requalified) — glucose-6-phosphate dehydrogenase zwf2 gnd2 (requalified) — decarboxylating 6-phosphogluconate dehydrogenase gnd2 rpiB (requalified) — ribose-5-phosphate isomerase B rpiB Rv1841c (family_assigned) — hemolysin family protein Rv1841c Rv1847 (family_assigned) — PaaI family thioesterase Rv1847 iniA (requalified) — isoniazid inductible protein IniA iniA glcB (requalified) — malate synthase G glcB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.