MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1787 · 46 genes shown · anchor PPE26 · open gene page → · ← back to 1 hop

Evidence: Min score 0
PPE25 (family_assigned) — PPE family protein PPE25 PPE25 PPE26 (family_assigned) — PPE family protein PPE26 PPE26 PE18 (family_assigned) — PE family protein PE18 PE18 Rv1786 (requalified) — ferredoxin Rv1786 Rv1794 (family_assigned) — ESX secretion-associated protein EspG Rv1794 PE25 (family_assigned) — PE family protein PE25 PE25 PE19 (family_assigned) — PE family protein PE19 PE19 esxN (requalified) — ESAT-6 like protein EsxN esxN esxA (requalified) — ESAT-6 protein EsxA esxA PE_PGRS33 (family_assigned) — PE-PGRS family protein PE_PGRS33 PE_PGRS33 adhA (family_assigned) — zinc-binding alcohol dehydrogenase family protein adhA rdgB (family_assigned) — RdgB/HAM1 family non-canonical purine NTP pyrophos rdgB Rv1352 (family_assigned) — hypothetical protein Rv1352 Rv3095 (family_assigned) — helix-turn-helix domain-containing protein Rv3095 PPE27 (family_assigned) — PPE family protein PPE27 PPE27 Rv3435c (family_assigned) — DUF4436 domain-containing protein Rv3435c Rv0245 (family_assigned) — flavin reductase family protein Rv0245 Rv0213c (requalified) — methyltransferase Rv0213c cyp143 (requalified) — cytochrome P450 cyp143 Rv3060c (family_assigned) — FCD domain-containing protein Rv3060c Rv0138 (family_assigned) — nuclear transport factor 2 family protein Rv0138 eccD5 (family_assigned) — type VII secretion system ESX-5 subunit EccD5 eccD5 eccD2 (family_assigned) — type VII secretion system ESX-2 subunit EccD2 eccD2 Rv3519 (family_assigned) — acetoacetate decarboxylase family protein Rv3519 PPE15 (family_assigned) — PPE family protein PPE15 PPE15 PPE41 (family_assigned) — PPE family protein PPE41 PPE41 PE8 (family_assigned) — PE family protein PE8 PE8 PPE43 (family_assigned) — PPE family protein PPE43 PPE43 PPE44 (family_assigned) — PPE family protein PPE44 PPE44 Rv2434c (requalified) — mechanosensitive ion channel Rv2434c Rv2432c (dark) — hypothetical protein Rv2432c nrtS (requalified) — nitrate/nitrite transporter NrtS nrtS Rv2435c (family_assigned) — adenylate/guanylate cyclase domain-containing prot Rv2435c PPE18 (family_assigned) — PPE family protein PPE18 PPE18 esxK (requalified) — type VII secretion system ESX-5 protein EsxJ esxK esxP (requalified) — type VII secretion system ESX-5 protein EsxJ esxP esxJ (requalified) — type VII secretion system ESX-5 protein EsxJ esxJ esxW (requalified) — type VII secretion system protein EsxW esxW esxO (requalified) — type VII secretion system effector EsxO esxO esxL (requalified) — type VII secretion system ESX-5 protein EsxL esxL esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 bacA (family_assigned) — vitamin B12 ABC transporter ATP-binding protein Ba bacA secA2 (requalified) — accessory Sec system translocase SecA2 secA2

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.