MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1786 · 46 genes shown · anchor cyp143 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1786 (requalified) — ferredoxin Rv1786 cyp143 (requalified) — cytochrome P450 cyp143 Rv3060c (family_assigned) — FCD domain-containing protein Rv3060c Rv0138 (family_assigned) — nuclear transport factor 2 family protein Rv0138 eccD5 (family_assigned) — type VII secretion system ESX-5 subunit EccD5 eccD5 eccD2 (family_assigned) — type VII secretion system ESX-2 subunit EccD2 eccD2 Rv3519 (family_assigned) — acetoacetate decarboxylase family protein Rv3519 fadE22 (requalified) — acyl-CoA dehydrogenase fadE22 Rv0771 (family_assigned) — carboxymuconolactone decarboxylase family protein Rv0771 Rv1874 (family_assigned) — hypothetical protein Rv1874 PPE25 (family_assigned) — PPE family protein PPE25 PPE25 Rv1006 (family_assigned) — hypothetical protein Rv1006 Rv1868 (family_assigned) — NAD(P)H-binding protein Rv1868 pks13 (requalified) — polyketide synthase Pks13 pks13 Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 mbtE (requalified) — peptide synthetase mbtE Rv2776c (requalified) — oxidoreductase Rv2776c cyp139 (requalified) — cytochrome P450 cyp139 ethR (family_assigned) — HTH-type transcriptional regulator EthR ethR Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 Rv0792c (family_assigned) — GntR family transcriptional regulator Rv0792c mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv3055 (family_assigned) — helix-turn-helix domain-containing protein Rv3055 Rv0139 (family_assigned) — NAD-dependent epimerase/dehydratase family protein Rv0139 Rv0140 (family_assigned) — DUF427 domain-containing protein Rv0140 msrA (requalified) — peptide-methionine (S)-S-oxide reductase MsrA msrA Rv0272c (family_assigned) — alpha/beta hydrolase Rv0272c Rv3906c (requalified) — pullulanase Rv3906c eccC5 (requalified) — ESX-5 type VII secretion system protein EccC5 eccC5 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 mycP5 (requalified) — type VII secretion system ESX-5 serine protease my mycP5 eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2 eccE5 (family_assigned) — type VII secretion system ESX-5 subunit EccE5 eccE5 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 mycP2 (requalified) — type VII secretion system ESX-2 serine protease my mycP2 Rv3888c (family_assigned) — MinD/ParA family protein Rv3888c eccA2 (family_assigned) — type VII secretion system ESX-2 AAA family ATPase eccA2 eccE2 (family_assigned) — type VII secretion system ESX-2 subunit EccE2 eccE2 Rv3899c (family_assigned) — hypothetical protein Rv3899c cyp142 (requalified) — steroid C26-monooxygenase Cyp142 cyp142 Rv3412 (dark) — DUF5319 domain-containing protein Rv3412 Rv0763c (requalified) — ferredoxin Rv0763c Rv1059 (requalified) — dihydrodipicolinate reductase Rv1059 fadB (requalified) — fatty oxidation protein FadB fadB ligB (requalified) — ATP-dependent DNA ligase ligB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.