MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1666c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
cyp139 (requalified) — cytochrome P450 cyp139 pks13 (requalified) — polyketide synthase Pks13 pks13 Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 Rv1667c (family_assigned) — Probable second part of macrolide-transport ATP-bi Rv1667c Rv1668c (family_assigned) — Probable first part of macrolide-transport ATP-bin Rv1668c mbtE (requalified) — peptide synthetase mbtE fdxB (requalified) — fatty acid desaturase fdxB cyp143 (requalified) — cytochrome P450 cyp143 cyp128 (requalified) — cytochrome P450 cyp128 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB rplF (requalified) — 50S ribosomal protein L6 rplF polA (requalified) — DNA polymerase I polA kshB (family_assigned) — 3-ketosteroid-9-alpha-hydroxylase reductase subuni kshB mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA gltD (family_assigned) — glutamate synthase subunit beta gltD ephB (requalified) — epoxide hydrolase EphB ephB ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1 rplU (requalified) — 50S ribosomal protein L21 rplU rplO (requalified) — 50S ribosomal protein L15 rplO rpsO (requalified) — 30S ribosomal protein S15 rpsO rplM (requalified) — 50S ribosomal protein L13 rplM mbtC (requalified) — polyketide synthetase MbtC mbtC mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG Rv1465 (family_assigned) — SUF system NifU family Fe-S cluster assembly prote Rv1465 iscS (family_assigned) — cysteine desulfurase family protein iscS pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mas (requalified) — mycocerosate synthase mas pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks12 (requalified) — type I polyketide synthase pks12 Rv2776c (requalified) — oxidoreductase Rv2776c Rv1786 (requalified) — ferredoxin Rv1786 Rv2267c (requalified) — sulfotransferase Rv2267c Rv2269c (family_assigned) — hypothetical protein Rv2269c ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA fadD26 (requalified) — long-chain-fatty-acid--AMP ligase FAAL26/FadD26 fadD26 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.