MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1598c · 46 genes shown · anchor mmpL5 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1598c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1598c mmpL5 (requalified) — siderophore RND transporter MmpL5 mmpL5 eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 mmpL9 (requalified) — RND transporter MmpL9 mmpL9 mmpL2 (requalified) — RND transporter MmpL2 mmpL2 mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 mmpL1 (requalified) — RND transporter MmpL1 mmpL1 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 Rv1303 (family_assigned) — ATP synthase subunit I Rv1303 hisC1 (requalified) — histidinol-phosphate aminotransferase hisC1 hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB Rv0756c (family_assigned) — hypothetical protein Rv0756c hisD (requalified) — histidinol dehydrogenase hisD mmpS5 (requalified) — siderophore transporter accessory protein MmpS5 mmpS5 mmpR5 (family_assigned) — siderophore transport transcriptional regulator Mm mmpR5 Rv3160c (family_assigned) — helix-turn-helix domain-containing protein Rv3160c eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 eccE3 (family_assigned) — type VII secretion system ESX-3 subunit EccE3 eccE3 mycP3 (requalified) — type VII secretion system ESX-3 serine protease my mycP3 espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 lppX (requalified) — LppX_LprAFG lipoprotein lppX Rv0128 (family_assigned) — YoaK family protein Rv0128 mmpS2 (family_assigned) — MmpS family protein mmpS2 Rv0508 (family_assigned) — glutaredoxin family protein Rv0508 hemA (requalified) — glutamyl-tRNA reductase hemA mmpS4 (requalified) — siderophore RND transporter accessory protein MmpS mmpS4 Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c mmpS1 (family_assigned) — MmpS family protein mmpS1 Rv1145 (requalified) — transmembrane transport protein Rv1145 eccA3 (requalified) — ESX-3 secretion system protein EccA eccA3 PPE4 (family_assigned) — PPE family protein PPE4 PPE4 atpB (family_assigned) — F0F1 ATP synthase subunit A atpB atpE (family_assigned) — F0F1 ATP synthase subunit C atpE atpF (family_assigned) — F0F1 ATP synthase subunit B atpF atpH (family_assigned) — F0F1 ATP synthase subunit B/delta atpH atpG (family_assigned) — F0F1 ATP synthase subunit gamma atpG atpA (family_assigned) — F0F1 ATP synthase subunit alpha atpA hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI phoP (requalified) — two-component system response regulator PhoP phoP phoR (requalified) — sensory box histidine kinase PhoR phoR Rv1125 (family_assigned) — WS/DGAT domain-containing protein Rv1125 lprB (family_assigned) — DUF3558 domain-containing protein lprB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.