MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1533 · 35 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1533 (family_assigned) — nitronate monooxygenase family protein Rv1533 Rv1534 (family_assigned) — TetR family transcriptional regulator Rv1534 fas (requalified) — fatty acid synthase fas Rv1532c (family_assigned) — PaaI family thioesterase Rv1532c mas (requalified) — mycocerosate synthase mas pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks12 (requalified) — type I polyketide synthase pks12 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB pks13 (requalified) — polyketide synthase Pks13 pks13 kasA (requalified) — 3-oxoacyl-ACP synthase KasA kasA fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD Rv0302 (family_assigned) — TetR/AcrR family transcriptional regulator Rv0302 Rv0238 (family_assigned) — TetR/AcrR family transcriptional regulator Rv0238 pth (requalified) — aminoacyl-tRNA hydrolase pth Rv3239c (requalified) — MFS transporter Rv3239c pks7 (requalified) — type I polyketide synthase pks7 pks17 (requalified) — polyketide synthase pks17 accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 pks6 (requalified) — membrane bound polyketide synthase pks6 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB papA1 (requalified) — acyltransferase PapA1 papA1 papA3 (requalified) — acyltransferase PapA3 papA3 papA2 (requalified) — trehalose-2-sulfate acyltransferase papA2 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 acpM (requalified) — meromycolate extension acyl carrier protein AcpM acpM fabH (requalified) — beta-ketoacyl-ACP synthase III fabH mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.