MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1526c · 46 genes shown · anchor pks5 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1526c (requalified) — glycosyltransferase Rv1526c pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 papA2 (requalified) — trehalose-2-sulfate acyltransferase papA2 papA1 (requalified) — acyltransferase PapA1 papA1 papA3 (requalified) — acyltransferase PapA3 papA3 cyp51 (requalified) — lanosterol 14-alpha demethylase cyp51 ureF (requalified) — urease accessory protein UreF ureF Rv0295c (family_assigned) — Stf0 family sulfotransferase Rv0295c pks1 (requalified) — polyketide synthase pks1 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB Rv1875 (requalified) — PPOX class F420-dependent oxidoreductase Rv1875 Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 Rv1728c (requalified) — glycoside hydrolase Rv1728c fas (requalified) — fatty acid synthase fas fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC mas (requalified) — mycocerosate synthase mas pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks13 (requalified) — polyketide synthase Pks13 pks13 mmpL8 (requalified) — sulfolipid-1 RND transporter MmpL8 mmpL8 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 mmpL10 (requalified) — RND transporter MmpL10 mmpL10 pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 cyp123 (requalified) — cytochrome P450 cyp123 Rv0762c (family_assigned) — nuclear transport factor 2 family protein Rv0762c Rv0763c (requalified) — ferredoxin Rv0763c Rv0765c (family_assigned) — SDR family oxidoreductase Rv0765c Rv0767c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0767c Rv0770 (requalified) — NAD(P)-dependent oxidoreductase Rv0770 ureD (requalified) — urease accessory protein UreD ureD ureG (requalified) — urease accessory protein UreG ureG ureC (family_assigned) — urease subunit alpha ureC ureA (family_assigned) — urease subunit gamma ureA ureB (family_assigned) — urease subunit beta ureB Rv1847 (family_assigned) — PaaI family thioesterase Rv1847 Rv0296c (requalified) — sulfatase Rv0296c lprB (family_assigned) — DUF3558 domain-containing protein lprB Rv0210 (family_assigned) — hypothetical protein Rv0210 Rv0180c (family_assigned) — YhgE/Pip domain-containing protein Rv0180c pks15 (requalified) — polyketide synthase pks15 mbtC (requalified) — polyketide synthetase MbtC mbtC mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtE (requalified) — peptide synthetase mbtE Rv1874 (family_assigned) — hypothetical protein Rv1874

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.