MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1485 · 45 genes shown · anchor hemY · open gene page → · ← back to 1 hop

Evidence: Min score 0
hemZ (requalified) — ferrochelatase hemZ hemY (requalified) — protoporphyrinogen oxidase hemY hemQ (requalified) — hydrogen peroxide-dependent heme synthase hemQ hemE (requalified) — uroporphyrinogen decarboxylase hemE Rv0958 (family_assigned) — ATP-binding protein Rv0958 mmcO (requalified) — multicopper oxidase MmcO mmcO Rv2850c (family_assigned) — magnesium chelatase subunit D family protein Rv2850c ctaB (requalified) — heme o synthase ctaB bfrB (requalified) — ferritin BfrB bfrB bfrA (requalified) — bacterioferritin BfrA bfrA inhA (requalified) — NADH-dependent enoyl-ACP reductase InhA inhA fabG1 (requalified) — 3-oxoacyl-ACP reductase FabG1 fabG1 hemC (requalified) — hydroxymethylbilane synthase hemC echA15 (family_assigned) — enoyl-CoA hydratase/isomerase family protein echA15 Rv2680 (dark) — DUF3000 domain-containing protein Rv2680 Rv2675c (requalified) — class I SAM-dependent methyltransferase Rv2675c hemD (requalified) — uroporphyrin-III C-methyltransferase hemD cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG Rv0959 (family_assigned) — VWA domain-containing protein Rv0959 purN (requalified) — phosphoribosylglycinamide formyltransferase purN purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH Rv0849 (requalified) — MFS transporter Rv0849 cysK2 (requalified) — cysteine synthase CysK cysK2 cobO (requalified) — cob(I)alamin adenosyltransferase cobO cobN (family_assigned) — cobaltochelatase subunit CobN cobN cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB ctaD (family_assigned) — cytochrome c oxidase subunit I ctaD ctaE (family_assigned) — heme-copper oxidase subunit III ctaE ctaC (family_assigned) — cytochrome c oxidase subunit II ctaC Rv1456c (requalified) — heme A synthase Rv1456c qcrB (family_assigned) — cytochrome bc complex cytochrome b subunit qcrB ahpC (requalified) — peroxiredoxin AhpC ahpC lpqL (family_assigned) — M28 family metallopeptidase lpqL Rv1770 (family_assigned) — hypothetical protein Rv1770 Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c Rv1877 (family_assigned) — MDR family MFS transporter Rv1877 Rv1879 (family_assigned) — amidohydrolase family protein Rv1879 fas (requalified) — fatty acid synthase fas accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 fabH (requalified) — beta-ketoacyl-ACP synthase III fabH kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC hemB (requalified) — porphobilinogen synthase hemB hemA (requalified) — glutamyl-tRNA reductase hemA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.