MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1394c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
cyp132 (requalified) — cytochrome P450 Cyp132 cyp132 Rv1393c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv1393c pks13 (requalified) — polyketide synthase Pks13 pks13 mbtE (requalified) — peptide synthetase mbtE Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 Rv1395 (family_assigned) — HTH-type transcriptional regulator Rv1395 fdxB (requalified) — fatty acid desaturase fdxB cyp128 (requalified) — cytochrome P450 cyp128 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB cyp123 (requalified) — cytochrome P450 cyp123 rplF (requalified) — 50S ribosomal protein L6 rplF polA (requalified) — DNA polymerase I polA kshB (family_assigned) — 3-ketosteroid-9-alpha-hydroxylase reductase subuni kshB nlhH (family_assigned) — alpha/beta hydrolase nlhH Rv1401 (family_assigned) — membrane protein Rv1401 Rv3741c (requalified) — oxidoreductase Rv3741c Rv3742c (requalified) — oxidoreductase Rv3742c mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 mbtC (requalified) — polyketide synthetase MbtC mbtC mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA gltD (family_assigned) — glutamate synthase subunit beta gltD ephB (requalified) — epoxide hydrolase EphB ephB ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1 Rv3833 (family_assigned) — helix-turn-helix transcriptional regulator Rv3833 Rv1190 (requalified) — alpha/beta fold hydrolase Rv1190 Rv3736 (family_assigned) — AraC family transcriptional regulator Rv3736 virS (family_assigned) — AraC family transcriptional regulator virS Rv1674c (family_assigned) — metalloregulator ArsR/SmtB family transcription fa Rv1674c Rv1465 (family_assigned) — SUF system NifU family Fe-S cluster assembly prote Rv1465 iscS (family_assigned) — cysteine desulfurase family protein iscS pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mas (requalified) — mycocerosate synthase mas pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks12 (requalified) — type I polyketide synthase pks12 Rv2267c (requalified) — sulfotransferase Rv2267c Rv2269c (family_assigned) — hypothetical protein Rv2269c Rv2776c (requalified) — oxidoreductase Rv2776c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.