MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1379 · 31 genes shown · anchor pyrB · open gene page → · ← back to 1 hop

Evidence: Min score 0
pyrR (family_assigned) — bifunctional pyr operon transcriptional regulator/ pyrR pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB pyrF (requalified) — orotidine-5'-phosphate decarboxylase pyrF pyrC (requalified) — dihydroorotase pyrC carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB carA (family_assigned) — glutamine-hydrolyzing carbamoyl-phosphate synthase carA Rv1382 (requalified) — transporter Rv1382 pyrH (requalified) — UMP kinase pyrH deoD (requalified) — purine-nucleoside phosphorylase deoD deoA (requalified) — thymidine phosphorylase deoA upp (requalified) — uracil phosphoribosyltransferase upp pyrE (requalified) — orotate phosphoribosyltransferase pyrE ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA pyrD (requalified) — quinone-dependent dihydroorotate dehydrogenase pyrD argG (requalified) — argininosuccinate synthase argG frr (requalified) — ribosome recycling factor frr atpH (family_assigned) — F0F1 ATP synthase subunit B/delta atpH ndkA (requalified) — nucleoside-diphosphate kinase ndkA tsf (requalified) — translation elongation factor Ts tsf cdd (requalified) — cytidine deaminase cdd pmmB (requalified) — phospho-sugar mutase pmmB apt (requalified) — adenine phosphoribosyltransferase apt add (requalified) — adenosine deaminase add hpt (requalified) — hypoxanthine phosphoribosyltransferase hpt deoC (requalified) — deoxyribose-phosphate aldolase deoC rpiB (requalified) — ribose-5-phosphate isomerase B rpiB guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA Rv0381c (dark) — hypothetical protein Rv0381c prsA (requalified) — ribose-phosphate diphosphokinase prsA Rv0385 (requalified) — FAD-binding oxidoreductase Rv0385 Rv1125 (family_assigned) — WS/DGAT domain-containing protein Rv1125

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.