MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1377c · 31 genes shown · anchor pyrR · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1377c (requalified) — class I SAM-dependent methyltransferase Rv1377c Rv1378c (family_assigned) — hypothetical protein Rv1378c pyrR (family_assigned) — bifunctional pyr operon transcriptional regulator/ pyrR pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB pyrF (requalified) — orotidine-5'-phosphate decarboxylase pyrF pyrC (requalified) — dihydroorotase pyrC Rv1382 (requalified) — transporter Rv1382 carA (family_assigned) — glutamine-hydrolyzing carbamoyl-phosphate synthase carA carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB Rv1367c (family_assigned) — hypothetical protein Rv1367c hemE (requalified) — uroporphyrinogen decarboxylase hemE hemQ (requalified) — hydrogen peroxide-dependent heme synthase hemQ hemY (requalified) — protoporphyrinogen oxidase hemY Rv3776 (family_assigned) — hypothetical protein Rv3776 Rv3074 (family_assigned) — DUF222 domain-containing protein Rv3074 Rv2633c (requalified) — non-heme di-iron catalase Rv2633c Rv1128c (family_assigned) — hypothetical protein Rv1128c pyrE (requalified) — orotate phosphoribosyltransferase pyrE pyrD (requalified) — quinone-dependent dihydroorotate dehydrogenase pyrD argG (requalified) — argininosuccinate synthase argG lipP (family_assigned) — serine hydrolase domain-containing protein lipP lipD (requalified) — lipase LipD lipD hemC (requalified) — hydroxymethylbilane synthase hemC hemZ (requalified) — ferrochelatase hemZ hemD (requalified) — uroporphyrin-III C-methyltransferase hemD cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG Rv2680 (dark) — DUF3000 domain-containing protein Rv2680 echA15 (family_assigned) — enoyl-CoA hydratase/isomerase family protein echA15 Rv2675c (requalified) — class I SAM-dependent methyltransferase Rv2675c Rv2850c (family_assigned) — magnesium chelatase subunit D family protein Rv2850c Rv0958 (family_assigned) — ATP-binding protein Rv0958

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.