MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1348 · 46 genes shown · anchor irtB · open gene page → · ← back to 1 hop

Evidence: Min score 0
irtA (family_assigned) — iron ABC transporter ATP-binding protein/permease irtA irtB (family_assigned) — iron ABC transporter ATP-binding protein/permease irtB mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA mbtI (requalified) — salicylate synthase mbtI Rv3402c (family_assigned) — DegT/DnrJ/EryC1/StrS family aminotransferase Rv3402c Rv0435c (family_assigned) — AAA family ATPase Rv0435c eccA3 (requalified) — ESX-3 secretion system protein EccA eccA3 dnaK (requalified) — molecular chaperone DnaK dnaK fabG2 (requalified) — 3-oxoacyl-ACP reductase FabG fabG2 eccA2 (family_assigned) — type VII secretion system ESX-2 AAA family ATPase eccA2 eccA1 (family_assigned) — type VII secretion system ESX-1 AAA family ATPase eccA1 Rv2688c (family_assigned) — ABC transporter ATP-binding protein Rv2688c mbtE (requalified) — peptide synthetase mbtE mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtC (requalified) — polyketide synthetase MbtC mbtC pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 entC (requalified) — isochorismate synthase entC mbtJ (requalified) — acetyl hydrolase mbtJ trpG (requalified) — anthranilate synthase component II trpG trpD (requalified) — anthranilate phosphoribosyltransferase trpD trpC (requalified) — indole-3-glycerol phosphate synthase TrpC trpC mbtK (requalified) — lysine N-acyltransferase MbtK mbtK pssA (requalified) — CDP-diacylglycerol--serine O-phosphatidyltransfera pssA psd (requalified) — phosphatidylserine decarboxylase psd moeA2 (requalified) — molybdopterin molybdenumtransferase moeA2 prcB (family_assigned) — proteasome subunit beta prcB eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 Rv0281 (requalified) — class I SAM-dependent methyltransferase Rv0281 PPE4 (family_assigned) — PPE family protein PPE4 PPE4 PE5 (family_assigned) — PE family protein PE5 PE5 espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 clpB (requalified) — chaperone protein ClpB clpB dnaJ1 (requalified) — chaperone protein DnaJ dnaJ1 grpE (requalified) — nucleotide exchange factor GrpE grpE dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 hspR (family_assigned) — heat shock transcriptional regulator HspR hspR htpG (requalified) — molecular chaperone HtpG htpG fas (requalified) — fatty acid synthase fas fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD Rv3538 (requalified) — dehydrogenase Rv3538 htdY (requalified) — 3-hydroxyacyl-thioester dehydratase HtdY htdY Rv0769 (family_assigned) — SDR family oxidoreductase Rv0769

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.